Clinical Takeaway Clinical trials show that cannabis-based products with higher THC content provide modest but measurable reductions in chronic pain compared to placebo. Evidence quality varies by product type, THC-to-CBD ratio, and...
Endocannabinoid System Research: Cannabis for PTSD and SUD
Clinical Takeaway People with PTSD and co-occurring substance use disorders who also use cannabis can still benefit meaningfully from trauma-focused treatments. Clinicians should not withhold or delay evidence-based PTSD care based on...
Endocannabinoid System Research: Cannabis in Family Medicine
Clinical Takeaway A randomized controlled trial tested the Minder mobile app, co-developed with university students, to address mental health and substance use challenges during the college transition period. Digital tools like this...
endocannabinoid system clinical research: athlete mental health
Clinical Takeaway Retired professional athletes from high contact team sports show notable rates of depression, anxiety, and other mental health challenges after leaving their sport. Factors such as head trauma history, loss...
Endocannabinoid Research: Cannabinoids for Children Review
Clinical Takeaway Systematic review evidence supports cautious, condition-specific use of cannabinoids in pediatric patients, with the strongest data in epilepsy and certain pain or palliative conditions. Safety and efficacy profiles vary considerably...
`Endocannabinoid System & Cannabis for Chronic Back Pain Trial`
Clinical Takeaway In this phase 3 trial of 820 adults with chronic low back pain, the full-spectrum cannabis extract VER-01 was evaluated against placebo over 12 weeks with extended follow-up reaching 15...
Cannabis-Based Products for Chronic Pain: Clinical Evidence
Clinical Takeaway Clinical trials show that cannabis-based products containing THC provide modest reductions in chronic pain compared to placebo, though the overall quality of evidence remains low to moderate. The benefit appears...
Endocannabinoid System & PTSD: Cannabis in Dual Diagnosis
Clinical Takeaway People with PTSD and co-occurring substance use disorders who use cannabis can still benefit meaningfully from trauma-focused treatments, and cannabis use does not appear to undermine treatment outcomes compared to...
Endocannabinoid System Research: Cannabis in Student Mental Health
Clinical Takeaway A randomized controlled trial tested the Minder mobile app, co-developed with university students, to address mental health and substance use challenges during the college transition period. Digital tools like Minder...
Endocannabinoid System Research in Athlete Mental Health
Clinical Takeaway Retired professional athletes from high contact team sports such as football, rugby, and hockey face elevated rates of depression, anxiety, and cognitive concerns compared to the general population. Career transition...