How PTSD affects oneโs social support system among veterans with cannabis dependence Military personnel are at high risk for exposure to traumatic events and later development of post-traumatic stress disorder (PTSD), in...
Interactive effects of PTSD and substance use on suicidal ideation and behavior in military personnel: Increased risk from marijuana use
Post-traumatic stress disorder (PTSD) is the most common mental disorder among active-duty soldiers and veterans, and is a major risk factor for suicidal thoughts and attempts in this population. As of 2018,...
Survey of herbal cannabis (marijuana) use in rheumatology clinic attenders with a rheumatologist confirmed diagnosis
Herbal cannabis has gained mainstream popularity as an effective therapy for many conditions, most noticeably pain. Because chronic pain is the most common and prominent symptom of rheumatic diseases - which include...
Synthetic cannabinoid Ajulemic acid exerts potent antifibrotic effects in experimental models of systemic sclerosis
The therapeutic potential of cannabinoids such as THC is grossly limited by their psychoactive effects, leading to a growing interest in the development of synthetic analogs with similar benefits but without activity...
Tapping into the endocannabinoid system to ameliorate acute inflammatory flares and associated pain in mouse knee joints
The cannabinoid system of the human body is composed of lipid molecules called endocannabinoids, cannabinoid receptors they bind to - namely CB1 and CB2, and enzymes - molecular machineries that synthesize and...
THC exposure of human iPSC neurons impacts genes associated with- neuropsychiatric disorders
The ever-increasing use of cannabis calls for a concerted effort to elucidate both positive and negative effects of this drug on human health. In particular, there is a strong correlation between cannabis...
The non-psychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
Many cannabinoids, the biologically active components of marijuana, are known to interact with and modulate humanโs immune system. Among the 2 major marijuana-derived cannabinoids, (ฮ9-tetrahydrocannabinol) THC also acts on humanโs brain and...
Recent meta-analysis demonstrates that CBD may be an effective treatment for MS
A recent study looks at the potential benefits of Cannabidiol for the treatment of multiple sclerosis (MS). The study looks at the immunomodulatory potential for such treatments. A salient takeaway from the...
Recent meta-analysis demonstrates that CBD has antioxidative and anti-inflammatory properties
A meta-analysis published in 2020 demonstrates that cannabidiol (CBD) may be beneficial for a number of diseases due to its effect on oxidative stress. More specifically, G-protein coupled receptors, along with their...
Cannabinomics: A novel approach to differentiating cannabis varieties
A recent study surveyed twenty varieties of cannabis using a novel technique that they refer to as cannabinomics. This technique employs mass spectrometry of the entire metabolome along with statistical analysis as...