Cannabidiol (CBD) has demonstrated positive effects against a wide spectrum of seizures. In fact, highly purified CBD has been approved...
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
Invasion and metastasis of aggressive breast cancer cells to other organs is the final and fatal step during cancer progression....
Safety and Tolerability of Cannabidiol in Parkinson Disease: An Open Label, Dose-Escalation Study
Parkinson disease (PD) is a neurodegenerative disorder very common among the older population. Since standard treatments often only partially relieve...
Self-reported Illicit Drug Use Among Norwegian University and College Students: Association with Age, Gender, and Geography
In many Western countries, illicit drug use has been purportedly prevalent among students in higher education, even more so than...
Stress, Emotional Intelligence and the Intention to Use Cannabis in Spanish Adolescence: Influence of COVID-19 confinement
The disease brought about by the SARS-CoV-2, COVID-19 coronavirus has had an unprecedented global impact. Confinement to control the outbreak...
Tetrahydrocannabinol-Rich Extracts From Cannabis Sativa L. Improve Glucose Consumption and Modulate Metabolic Complications Linked to Neurodegenerativ
Tetrahydrocannabinol (THC), a major constituent of the plant cannabis, can interact with endocannabinoid receptors abundant on neurons, thereby affecting multiple...
Association Between Marijuana Use and Cardiovascular Disease in US Adults
The prevalence of marijuana use has risen steadily for the past decade, reaching approximately 200 million consumers worldwide. At the...
Anti-obesity therapy with peripheral CB1 blockers: from promise to safe practice
Pharmacological blockers of the cannabinoid receptor type-1 (CB1) were shown in both research and clinical settings to deliver highly efficient...
Inverse Agonism of Cannabinoid Receptor Type 2 Confers Anti-inflammatory and Neuroprotective Effects Following Status Epileptics
When the brain is attacked by infections, microglia, the immune cells that reside inside and regulate inflammation in the brain,...
Adolescent CB1 receptor antagonism influences subsequent social interactions and neural activity in female rats
The endogenous cannabinoid system (ECS), which consists of endocannabinoids - signalling lipid molecules, cannabinoid receptors CB1 and CB2 that they...