Satiety Bypass: How Cannabis Overrides the Brain’s ‘I’m Full’ Signal

A massive study tracking over 460,000 teens found that cannabis use during adolescence doubled the risk of psychotic and bipolar disorders, underscoring why age restrictions and youth prevention are critical. Neuroscience News deep-dive into the WSU/Calgary PNAS study on cannabis-induced appetite. THC activates CB1 receptors in the hypothalamus to override natural satiety signals, creating a feeling of starvation even in recently fed subjects.

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Cannabis: What Is the Profile of Adults at Low Risk of Dependence?

Scientists have mapped exactly how THC tricks your brain into feeling starving even when you’re full, which opens the door to developing appetite-boosting medications without the psychoactive high. A University of Montreal study published in the Journal of Cannabis Research found that among Quebec adults in their mid-30s who used cannabis in the past year, 63% were at low risk for cannabis use disorder (CUD). Lower-risk users tended to use cannabis occasionally and in social contexts, and were more likely to be women or to co-use cannabis with alcohol rather than tobacco.

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Medical Cannabis Improves Sleep for Insomnia Patients

Most cannabis usersโ€”63%โ€”are at low risk for developing dependence, which means public health policy should acknowledge that the majority of adults use cannabis without developing a problem. NORML reports on data from the UK Medical Cannabis Registry showing that insomnia patients who consume cannabis-based medicinal products (CBMPs) report sustained improvements in sleep quality over 18 months. Among 124 patients assessed at multiple intervals, cannabis use was associated with better sleep, reduced anxiety, and improved health-related quality of life.

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Cannabis-Related ‘Munchies’ Are Real, and Could Help People with AIDS, Cancer

If you struggle with insomnia, this data shows medical cannabis provided sustained sleep improvement for 18 months, with nearly 40% of patients reducing or quitting their prescription sleep medications. A collaborative study by WSU and University of Calgary, published in PNAS, confirms ‘the munchies’ are a real cognitive response that occurs regardless of sex, age, weight, or recent food consumption. In a randomized clinical trial of 82 volunteers who vaped 20 or 40mg of cannabis or placebo, intoxicated participants ate significantly more food within the first 30 minutes.

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When Legalization Meets Reality: High-THC Cannabis and Psychosis Risk

Scientists have proven that cannabis-triggered appetite is a real brain responseโ€”not just a stereotypeโ€”which could lead to life-saving treatments for patients with HIV/AIDS and cancer who can’t eat. Psychology Today analysis examines the tension between cannabis legalization and emerging mental health research. THC potency has risen dramatically since the 1990s, with vape cartridges now near-pure levels.

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Study: Minor Cannabinoids CBDV and CBG Show Powerful Anti-Inflammatory Effects When Combined

If you or someone you love uses high-potency cannabis products regularly, this research suggests the mental health risks are realโ€”especially for younger users whose brains are still developing. A study published in the Journal of Ethnopharmacology found that 10 non-psychotropic phytocannabinoidsโ€”particularly CBDV and CBGโ€”demonstrated meaningful anti-inflammatory effects. Researchers from the University of Chemistry and Technology and the Czech Academy of Sciences found that CBDV significantly reduced IL-6 and TNF-ฮฑ production and inhibited NF-ฮบB activation.

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United Center Becomes First Major US Arena to Partner with Cannabis Drink Brands

New research shows that combining lesser-known cannabinoids like CBDV and CBG produces stronger anti-inflammatory effects than any single compound alone, supporting the value of full-spectrum hemp products. Chicago’s United Center, the largest entertainment arena in the US, has entered a historic partnership with cannabis drink brands, establishing the first-ever official THC sponsorship at a major American venue. The deal with RYTHM Inc.

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Hawaii Senators Approve Limited Marijuana Legalization Bill After House Punts for 2026

A cannabis beverage brand sponsoring a major NBA arena signals that these products are becoming as mainstream as beerโ€”yet the federal ban could eliminate them just as they achieve cultural acceptance. Hawaii senators have taken up a pair of bills to legalize marijuana, with one proposal contingent on federal reform or changes to the state Constitution. The Senate’s advancement comes after the House punted on reform for 2026.

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Cannabis Industry Wage Crisis: Minimum Wage Catching Up to Once-Premium Jobs

Hawaii joining the growing list of states advancing cannabis legalization means more Americans may soon have access to regulated, tested cannabis products regardless of where they live. The cannabis industry, once known for above-average pay, is falling behind as minimum wages rise in 22 states and dozens of cities. Price compression and debt are forcing operators to make difficult choices about compensation.

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Massachusetts Surpasses $9 Billion in Adult-Use Cannabis Sales Since 2018 Launch

The people who help you choose the right cannabis productsโ€”budtenders with specialized training in cannabinoids and terpenesโ€”are seeing their wages fall toward minimum wage as the industry faces economic pressure. Massachusetts officials announced the state has surpassed $9 billion in adult-use cannabis purchases since the market launched in 2018, a major milestone for one of the East Coast’s earliest recreational markets. Record January snowfall drove record monthly salesโ€”exceeding even the traditional 4/20 holiday peak.

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