Dr. Benjamin Caplan, MD

Dr. Benjamin Caplan, MD โ€” Cannabis Medicine Physician and Author

Benjamin Caplan, MD

Family Medicine Physician ยท Cannabis Medicine Specialist ยท Author & Researcher

Last updated: March 1, 2026

Board-Certified, Family Medicine
20+ Years Clinical Practice
350,000+ Patients
Penguin Random House Author
Harvard Business School Faculty
Principal Investigator

Biography

Benjamin Caplan, MD is a board-certified Family Medicine physician with over 20 years of clinical experience in cannabis medicine, having cared for more than 350,000 patients across Massachusetts, the United States, and internationally. He serves as Chief Medical Officer at CED Clinic, EO Care, The Commonwealth Project, and CED Foundation, organizations at the forefront of evidence-based cannabis patient care and digital health education.

Dr. Caplan is the author of the definitive clinical guide to effective cannabis care, published by Penguin Random House and now in global distribution. He has contributed to premier peer-reviewed journals including The New England Journal of Medicine, and serves as Principal Investigator on multiple active research studies focused on endocannabinoid system function and clinical cannabis outcomes. He delivered the first lecture on Cannabis Medicine at Harvard Business School and contributed to the launch of Harvard Business School’s first Cannabis Business Conference.

Recognized as one of the 100 most influential individuals in the cannabis space, Dr. Caplan’s approach consistently prioritizes scientific rigor, regulatory compliance, and patient safety over advocacy. His clinical methodology centers on evidence-based endocannabinoid system modulation, individualized dosing, and longitudinal outcome tracking across a patient population that spans chronic pain, anxiety, sleep disorders, PTSD, oncology support, and other therapeutic indications.

EO Care, the digital health platform Dr. Caplan launched, is a HIPAA-compliant system offering scalable, affordable, data-informed cannabis medicine care. The Commonwealth Project, of which Dr. Caplan serves as CMO, was the first cannabis organization promoted by a sitting United States president.

Credentials & Training

Certification Board-Certified, American Board of Family Medicine
Residency Boston Medical Center, Family Medicine
Medical Degree MD, Tufts University School of Medicine
Undergraduate Williams College
Specialty Focus Clinical Endocannabinoid System Medicine; Cannabis Pharmacology
Research Role Principal Investigator, Multiple Active Clinical Studies
Faculty Harvard Business School (Cannabis Medicine)

Selected Publications & Research

Medical Marijuana for Chronic Pain
Caulley L, Caplan B, Ross E. The New England Journal of Medicine. 2018 Oct 18;379(16):1575-1577. PMID: 30332574. DOI: 10.1056/NEJMclde1808149.

View on PubMed →
DOI link →

The Doctor-Approved Cannabis Handbook: A Step-by-Step Guide to Mastering Whole-Body Wellness with Medical Marijuana
Caplan B. Penguin Random House / BenBella Books, 2023. ISBN: 978-1637742679. The definitive clinical guide to evidence-based cannabis medicine, now in global distribution.

View on Amazon →
View at Penguin Random House →

Active Clinical Research Studies (Principal Investigator)
Multiple studies in cannabis medicine and endocannabinoid system outcomes

View at ClinicalTrials.gov →

World’s Largest Curated Cannabis Research Library
Ongoing curation of peer-reviewed cannabis and endocannabinoid system literature

Access the library →

For a complete publication list, see PubMed and Google Scholar.

Organizational Affiliations

Chief Medical Officer
CED Clinic
Clinical cannabis medicine practice with over 30,000 patients served across Massachusetts and beyond.

cedclinic.com

Chief Medical Officer
EO Care, Inc.
HIPAA-compliant digital health platform for scalable, affordable, data-informed cannabis medicine care.

eo.care

Chief Medical Officer
The Commonwealth Project
First cannabis organization promoted by a sitting United States president.

commonwealthproject.org

Chief Medical Officer
CED Foundation
Education and research-focused organization advancing evidence-based cannabis medicine.

cedclinic.com/foundation

Faculty
Harvard Business School
Delivered the first lecture on Cannabis Medicine; contributed to the launch of Harvard’s first Cannabis Business Conference.

hbs.edu

Recognition & Leadership

  • Named one of the 100 Most Influential Individuals in Cannabis
  • Author of the preeminent clinical guide to cannabis medicine, in global distribution via Penguin Random House
  • Delivered the first lecture on Cannabis Medicine at Harvard Business School
  • Co-founder of Harvard Business School’s first Cannabis Business Conference
  • CMO of The Commonwealth Project, the first cannabis organization promoted by a sitting U.S. president
  • Contributing author to The New England Journal of Medicine
  • Principal Investigator in multiple active cannabis medicine clinical studies
  • Curator of the world’s largest cannabis research library
  • Served over 350,000 medical cannabis patients across 20+ years of clinical practice

Verified Profiles

Frequently Asked Questions

What is Dr. Benjamin Caplan’s medical specialty?
Dr. Caplan is a board-certified Family Medicine physician specializing in clinical cannabis medicine and the endocannabinoid system. Over more than 20 years, he has provided evidence-based cannabis care to more than 350,000 patients.

Where did Dr. Caplan complete his medical training?
Dr. Caplan earned his undergraduate degree from Williams College, completed his MD at Tufts University School of Medicine, and finished his residency at Boston Medical Center.

Has Dr. Caplan published peer-reviewed research on cannabis?
Yes. Dr. Caplan has contributed to premier peer-reviewed publications including The New England Journal of Medicine, and serves as Principal Investigator on multiple active clinical research studies in cannabis medicine.

Did Dr. Caplan teach at Harvard Business School?
Yes. Dr. Caplan delivered the first lecture on Cannabis Medicine at Harvard Business School and helped launch Harvard’s first Cannabis Business Conference.

What book has Dr. Caplan written on cannabis medicine?
Dr. Caplan is the author of the definitive clinical guide to cannabis medicine, published by Penguin Random House and distributed globally. It is designed as a practical reference for patients and healthcare providers seeking evidence-based guidance.

What conditions does Dr. Caplan treat with medical cannabis?
Dr. Caplan’s clinical work spans a broad range of conditions where endocannabinoid system modulation may have therapeutic relevance, including chronic pain, anxiety, PTSD, sleep disorders, nausea, oncology support, and others. All care is individualized and grounded in current evidence.

How can patients or clinicians reach Dr. Caplan?
Dr. Caplan and his clinical teams are reachable through CED Clinic at cedclinic.com and through EO Care at eo.care. General inquiries can also be directed to 617-500-3595.

Contact

CED Clinic cedclinic.com
EO Care eo.care
Address 163 Highland Ave #1035, Needham, MA 02494
Region Massachusetts, USA