Clinical Takeaway Clinical Takeaway: Adolescents experiencing depression and anxiety symptoms demonstrate increased risk for cannabis initiation and escalated use patterns, suggesting these psychiatric conditions represent a genuine vulnerability pathway rather than coincidental...
Endocannabinoid System: Anxiety, Depression and Cannabis Use
Clinical Takeaway Adolescents with depression and anxiety symptoms show increased cannabis use over 18 months, suggesting self-medication behavior in vulnerable populations. This longitudinal evidence indicates that mental health screening and early intervention...
Endocannabinoid System Research: Cannabis Use in Teen Anxiety
Clinical Takeaway Adolescents experiencing depression, generalized anxiety, social anxiety, or panic symptoms are more likely to initiate and increase cannabis use over time, suggesting these internalizing conditions may drive substance use as...
Most European Countries Lack Evidence-Based Cannabis-Specific Treatment
Sixteen countries reported the existence of specific cannabis-specific programs. Fifteen countries provided specific face-to-face interventions, which mostly have limited national coverage. Most programs are not evidence-based.
Selective Personality-Targeted Intervention and the Escalation of Substance Use During Adolescence: A Secondary Analysis of A Cluster-Randomized Clinical Trial.
Substance use is a leading cause of burden of disease worldwide. Selective prevention programs can help reduce the development of problematic substance use a…
`Endocannabinoid System & Adolescent Cannabis Use Risk`
Clinical Takeaway Adolescents with higher levels of depression and anxiety symptoms show increased likelihood of initiating and using cannabis more frequently over time, supporting the self-medication hypothesis in this age group. This...
Small Pilot Trial Finds Medicinal Cannabis Feasible to Study in Adolescents with Tourette Syndrome — But Efficacy Remains Unknown
The findings suggest that the study protocol is feasible and acceptable to patients with TS and their families. A fully powered study is needed to evaluate the efficacy of MC in adolescent TS.
`Endocannabinoid System Research: Adolescent Eating & Mental Health`
Clinical Takeaway Eating disorders and disordered body image in adolescence are linked to lasting mental health and substance use challenges into early adulthood. This 15-year Canadian cohort study tracked these trajectories to...
`Cannabinoid Clinical Trials: Cannabis Interventions for Teens`
Clinical Takeaway Scare-tactic cannabis prevention campaigns often fail because teens hold widely different beliefs about the drug, and a one-size-fits-all message rarely lands. This research tested a smarter approach: when a teen...
Endocannabinoid System & Teen Mental Health Risk Factors
Clinical Takeaway Adolescents with depression, generalized anxiety, social anxiety, and panic symptoms were more likely to initiate and increase cannabis use over an 18-month follow-up period. This longitudinal evidence supports the self-medication...