Research studies, summarized and reviewed by Dr. Benjamin Caplan, MD¹ (Page 5)

Researchers studied 33 healthy young adults in their early twenties who used cannabis occasionally. Each person took a capsule with a moderate amount of synthetic THC (the main intoxicating ingredient in cannabis, given as a prescription form) on one visit and an inactive capsule on another, and their brain activity was scanned at rest while they were high.

This is a review article about older adults, meaning people aged 50 and up, who use cannabis to help them sleep. The authors looked at what research already exists and what is still missing. They did not run a new study with patients.

Twenty healthy adults took a hemp-derived oil product that contains a substance called cannabidiol, either by mouth or rubbed onto the skin, at different times. Blood was drawn over the following day to see how much of the substance entered the body by each route.

This study followed 192 adults in the United Kingdom who had long-lasting pain from arthritis and were given medicinal cannabis by a private clinic. Each person filled in questionnaires about pain, mood, sleep and daily life over two years. The researchers looked at how these answers changed over time.

This review pooled results from many earlier studies of a mouth spray containing two cannabis compounds, called nabiximols, in adults with multiple sclerosis. The researchers looked at whether it helped with problems other than the muscle stiffness it is already approved for, such as bladder, sleep, muscle spasms and walking.

This study looked at the list of research projects that have been registered on a public website that tracks medical studies. It counted the cannabis-based treatments being tested, the health problems they aim to address, and how big and how long the studies tend to be.

Researchers pooled results from 43 earlier surveys covering almost 390,000 people, mostly in the United States and Europe. They looked at how many people had ever used, or recently used, a product made from the non-intoxicating part of cannabis, called cannabidiol (CBD), and compared North America with Europe.

This study looked at how safe it is for people who drink alcohol moderately to also use a substance called cannabidiol (CBD). The researchers tested this in two settings: a lab and in people's homes over a longer period.

This review looked at how medical treatments that were recently made legal get put into real healthcare settings, such as assisted dying, medication abortion and medical cannabis. The researchers gathered and sorted a large number of published studies to find what helped and what got in the way.

This review looked at many earlier studies to see whether using CBD products or hemp oil can cause a person to fail a drug test for cannabis. Most of the studies involved adult volunteers or patient reports, and they tested blood, urine, saliva and hair samples.