Age differences in endocannabinoid tone are ameliorated after recent cannabis use
Older adults demonstrate diminished baseline levels of specific endocannabinoids and NAEs (AEA, DEA, LEA).
Cannabinoids and Pain for the Plastic Surgeon
While preclinical and early human studies suggest that oral and topical CBD may offer safe, adjunctive pain relief with minimal side effects.
Acute effects of cannabigerol on anxiety, stress, and mood: a double-blind, placebo-controlled, crossover, field trial
Cannabigerol (CBG) may be a promising option for reducing anxiety and stress in healthy adults without causing impairment or significant side effects.
Cannabinoid therapeutics in orofacial pain management: a systematic review
While current systemic and oral cannabinoid formulations lack robust evidence for managing acute orofacial and post-operative dental pain.
A double-blind, randomized, placebo-controlled study of the safety and effects of CBN with and without CBD on sleep quality.
Administering 20 mg of isolated cannabinol (CBN) nightly can effectively reduce nighttime awakenings and overall sleep disturbance in patients with.
Acute Effects of Oral Cannabinoids on Sleep and High‐Density EEG in Insomnia: A Pilot Randomised Controlled Trial
Consider the use of oral cannabinoids as a potential treatment option for patients with insomnia.
Evaluating the impact of cannabinoids on sleep health and pain in patients with chronic neuropathic pain: a systematic review and meta-analysis of randomized controlled trials
Clinicians should consider the potential benefits of cannabinoids for improving sleep in patients with chronic neuropathic pain.
Cannabis and Cannabinoids in Adults With Cancer: ASCO Guideline
Clinicians should consider the use of cannabis and cannabinoids as part of a comprehensive treatment plan for cancer patients.
Adverse events caused by cannabinoids in middle aged and older adults for all indications: a meta-analysis of incidence rate difference
Clinicians should be cautious when prescribing cannabinoid-based medicines to older adults due to the limited data on adverse events.
Association of CNR1 gene and cannabinoid 1 receptor protein in the human brain
The study highlights the importance of understanding the relationship between gene and protein expression for the CB1 receptor.
