Acute and Extended Anxiolytic Effects of Cannabidiol in Cannabis Flower: A Quasi-Experimental ad libitum Use Study
Consider recommending CBD-dominant cannabis for patients with anxiety symptoms, as it may provide greater relief compared to THC-dominant options.
A Preliminary Pharmacokinetic Comparison of Δ-9 Tetrahydrocannabinol and Cannabidiol Extract Versus Oromucosal Spray in Healthy Men and Women
Clinicians should consider the route of administration when prescribing THC:CBD formulations, as bioavailability may vary significantly between methods.
A randomized, placebo-controlled, double-blind, pilot study of cannabis-related driving impairment assessed by driving simulator and self-report
Clinicians should be aware of the potential driving impairments associated with cannabis use and advise patients accordingly.
A Randomized Controlled Trial of the Safety and Efficacy of Dronabinol for Agitation in Alzheimer’s Disease
Consider dronabinol as a potential treatment option for managing agitation in Alzheimer's disease.
Cannabis dosing and administration for sleep: a systematic review
Integrative physicians should consider cannabis as a potential treatment for sleep disorders, while paying close attention to dosing to maximize benefits.
Acute Effects of Oral Cannabinoids on Sleep and High‐Density EEG in Insomnia: A Pilot Randomised Controlled Trial
Consider the use of oral cannabinoids as a potential treatment option for patients with insomnia.
Acute metabolic effects of cannabinoid receptor modulators during sequential hyperglycemic, euglycemic-hyperinsulinemic clamps in healthy individuals
In healthy men, acute administration of the cannabinoid receptor agonist nabilone enhanced peripheral insulin sensitivity while reducing fasting.
A Pilot Randomized Placebo-Controlled Crossover Trial of Medicinal Cannabis in Adolescents with Tourette Syndrome
This pilot study indicates that medicinal cannabis may be a feasible treatment option for adolescents with Tourette Syndrome.
Adverse events caused by cannabinoids in middle aged and older adults for all indications: a meta-analysis of incidence rate difference
Clinicians should be cautious when prescribing cannabinoid-based medicines to older adults due to the limited data on adverse events.
Acute Effects of Cannabis on Alcohol Craving and Consumption: A Randomized Controlled Crossover Trial
Clinicians should be aware of the complex relationship between cannabis use and alcohol consumption.