Research studies, summarised and reviewed by a physician

Research study

Cannabinoid-based interventions for behavioral outcomes in children and adolescents with autism spectrum disorder: A systematic review of safety and effectiveness

While observational studies and one RCT suggest modest behavioral and social communication benefits from full-spectrum.

Research study

Cannabis and cannabidiol for postoperative pain management in orthopedic surgery: a scoping review

Current clinical evidence regarding the use of cannabinoids for postoperative pain in orthopedic surgery remains inconclusive due to significant trial.

Research study

Acute Effects of Cannabis on Alcohol Craving and Consumption: A Randomized Controlled Crossover Trial

Clinicians should be aware of the complex relationship between cannabis use and alcohol consumption.

Research study

Acute behavioural effects of low-dose cannabidiol: A randomised crossover trial in healthy volunteers

Clinicians should be cautious when recommending low-dose CBD products, as the evidence for their effects is still inconclusive.

Research study

A Synthetic Form of Cannabinoid Does Not Decrease Opioid Use After Total Knee Arthroplasty: A Prospective, Randomized, Triple-Blind, Placebo-Controlled Study

In this prospective, triple-blind, placebo-controlled trial, oral dronabinol (2.5 mg twice daily) failed to reduce opioid consumption or improve secondary.

Research study

Preoperative Oral Cannabidiol-Rich Cannabis Extract for Anxiety and Postoperative Pain After Endodontic Treatment

A double-blind trial testing whether a CBD-rich extract taken before a root canal reduced anxiety during the procedure or pain afterwards.

Research study

Short-Term Cannabidiol with Δ-9-Tetrahydrocannabinol in Parkinson’s Disease: A Randomized Trial

A short randomised trial of a high-CBD, low-THC oral extract in 61 people with Parkinson's disease, a group who use cannabis often despite thin evidence.

Research study

Medicinal Cannabis for Symptom Control in Advanced Cancer: A Randomised, Placebo-Controlled Trial of 1:1 THC and CBD

A placebo-controlled trial asking whether a 1:1 THC:CBD oil eased the overall symptom burden of advanced cancer beyond what palliative care already.

Research study

Tetrahydrocannabinol and Cannabidiol in Tourette Syndrome

A crossover trial in which 22 people with severe Tourette syndrome took both an oral THC/CBD oil and a placebo, six weeks each.

Research study

Oral Cannabis Extract for Chemotherapy-Induced Nausea and Vomiting: A Randomized, Placebo-Controlled Phase II/III Trial

A randomised trial in adults who were still being sick during chemotherapy despite already taking the standard anti-sickness medicines.