Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
Cannabidiol as a novel inhibitor of Id-1 gene expression shows promise in reducing the invasiveness of aggressive breast cancer cells. This focus on cannabidiol as a novel inhibitor of Id-1 gene expression highlights its potential therapeutic role.…
Safety and Tolerability of Cannabidiol in Parkinson Disease: An Open Label, Dose-Escalation Study
Parkinson disease patients often seek alternative treatments like cannabidiol. This study investigates the safety and tolerability of cannabidiol in Parkinson disease. Results show mild adverse events and potential symptom improvement.
Self-reported Illicit Drug Use Among Norwegian University and College Students: Association with Age, Gender, and Geography
Self-reported illicit drug use among Norwegian university students has shown notable trends by age, gender, and geography. The study highlights increased drug use prevalence from 2014 to 2018. These findings emphasize the importance of addressing student…
Stress, Emotional Intelligence and the Intention to Use Cannabis in Spanish Adolescence: Influence of COVID-19 confinement
The study on stress and cannabis use adolescents during COVID-19 confinement reveals increased stress levels but no immediate rise in cannabis use intention. Emotional intelligence was found to protect against cannabis consumption among teens. These…
Tetrahydrocannabinol-Rich Extracts Enhance Brain Glucose Consumption and Metabolic Modulation
Tetrahydrocannabinol brain glucose consumption plays a crucial role in modulating metabolic complications linked to neurodegenerative diseases. THC-rich extracts from Cannabis Sativa L. improve glucose uptake and reduce oxidative stress in brain tissue.…
Association Between Marijuana Use and Cardiovascular Disease in US Adults
The prevalence of marijuana use has increased globally, raising questions about its cardiovascular effects. Recent studies examine marijuana use and cardiovascular disease risk in US adults. This article reviews findings on marijuana use and…
Anti-Obesity Therapy with Peripheral CB1 Blockers: From Promise to Safe Practice
Peripheral CB1 blockers obesity therapy offers a promising approach to weight management by targeting cannabinoid receptors outside the brain. These blockers reduce fat intake and improve metabolism with fewer psychiatric side effects. Research continues…
Inverse Agonism of Cannabinoid Receptor Type 2 Confers Neuroprotection After Status Epileptics
Cannabinoid receptor type 2 anti-inflammatory activity plays a key role in reducing brain inflammation after status epilepticus. Activation of CB2 receptors in microglia helps protect neurons from damage. This mechanism offers promising neuroprotective…
Adolescent CB1 Receptor Antagonism Influences Social Interactions and Neural Activity in Female Rats
Adolescent CB1 receptor antagonism plays a crucial role in shaping social interactions and neural activity in female rats. This study highlights sex-specific effects of CB1 receptor inhibition during adolescence. Findings suggest important implications…
Reduction of Benzodiazepine Use in Patients Prescribed Medical Cannabis
Benzodiazepine discontinuation rates have been studied in patients prescribed medical cannabis therapy. Research shows a significant reduction in benzodiazepine use over time with cannabis treatment. Understanding these rates helps evaluate the benefits…
