placebo-controlled crossover trial

First Placebo-Controlled Trial of Cannabigerol Finds Reduced Anxiety and Stress—But With Important Caveats

By Benjamin Caplan, MD

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May 8, 2026

9 Min Read

The 2024 CBG anxiety stress trial found that a single 20 mg dose of cannabigerol reduced anxiety and stress in healthy adults without intoxication. This placebo-controlled study provides the first controlled human evidence supporting CBG's anxiolytic…