This Evidence Watch article reviews a 2026 systematic evidence update on adolescent substance use treatment. The review found that family-based therapy, CBT, motivational approaches, and multicomponent behavioral care remain the best-supported outpatient options, while cannabis-specific and opioid-specific adolescent evidence remains limited. The main caution is that the paper updates the evidence base rather than testing a new intervention, so its strongest value is clinical framing, not a new treatment breakthrough.