Clinical safety monitoring

Schedules of Controlled Substances: Temporary Placement of N-pyrrolidino metonitazene and N-pyrrolidino protonitazene in Schedule I

By Benjamin Caplan, MD

Comments Off on Schedules of Controlled Substances: Temporary Placement of N-pyrrolidino metonitazene and N-pyrrolidino protonitazene in Schedule I

March 8, 2026

3 Min Read

Nitazene synthetic opioids such as N-pyrrolidino metonitazene and N-pyrrolidino protonitazene have been temporarily placed in Schedule I. These substances pose significant overdose risks and are emerging threats in illicit drug supplies. Clinicians…