Cannabinoid receptor type 1 antagonist inhibits progression of obesityโassociated nonalcoholic steatohepatitis in a mouse model by remodulating immune system disturbances In Summary: Steatohepatitis, a condition often associated with type 2 diabetes and...
A promising cure for PTSD: Cannabis-based medicine suppresses aversive memory and eases anxiety
Effects of ฮ9-tetrahydrocannabinol on aversive memories and anxiety: a review from human studies In Summary: โ Post traumatic stress disorder (PTSD) is a mental disorder that arises after a person experiences or...
Cannabidiol: Attenuation of behavioral and cognitive schizophrenia symptoms leads to potential clinical applications
Cannabidiol attenuates behavioral changes in a rodent model of schizophrenia through 5-HT1A, but not CB1 and CB2 receptors In Summary Although cannabidiol (CBD), a major constituent of the plant cannabis, is known...
The wide distribution of cannabinoid receptors in the gastrointestinal tract suggests cannabinoids like CBD can relieve GI pain
Localization of cannabinoid and cannabinoid related receptors in the cat gastrointestinal tract โIn Summary Cannabidiol (CBD) is a component of the plant cannabis with great potential for medical applications because of its...
Neurological and neurodegenerative conditions, physical activities, and the endocannabinoid system โ how might all these be linked?
Can physical activity support the endocannabinoid system in the preventive and therapeutic approach to neurological disorders? In Summary The endocannabinoid signaling system (ECS) of the body includes naturally produced chemicals called cannabinoids,...
Activation of a cannabinoid receptor represents a promising therapeutic strategy for Parkinson’s Disease
Activation of CB2R with AM1241 ameliorates neurodegeneration via the Xist/miR-133b-3p/Pitx3 axis โIn Summary Schematic representation showing the proposed mechanism by which the CBR2 agonist AM1241 exerts neuroprotective effects through the Xist/ miR-133b-3p/Pitx3...
Targeting the endocannabinoid system for stroke prevention
Endocannabinoids and Stroke Prevention: Review of Clinical Studies In Summary Ischemic stroke is a very common medical emergency with 15 million new cases worldwide annually. Its consequences are severe, usually causing permanent...
FDA hesitant to approve more CBD based products
FDA Warns of Potential Harm From CBD Products In Summary The spread of misinformation is one of the scariest things in the 21st century. As more and more people become exposed to...
What is The Entourage Effect?
By Lilly Bertone Before we dive deeply into the different terpenes and cannabinoids found in the cannabis plant, itโs important to first talk about The Entourage Effect. Along with THC, the cannabis...
New Opportunities Arise as Cannabis is Legalized in Canada
"Tea" Time? Cannabis Legalization in Canada In Summary Last summer an op-ed came out in response to cannabis legalization in Canada discussing the risks and benefits of the legalization. The author acknowledges...