#85 Research Authority
Peer-reviewed research curated for clinical relevance and evidence quality.
Recent research digest. 20 of 20 most recent studies from our monitored feeds.
Impact of Cannabis Edibles Combined With Alcohol on Driving, Field Sobriety Performance, and Subjective Effects: A Within-Participant Crossover Trial.
Zamarripa C Austin et al.
JAMA network open
• 2026
IMPORTANCE: Simultaneous cannabis and alcohol use (co-use) is a public safety concern. Controlled data on the effects of co-ingestion of oral cannabis…
Cannabis use and atrial arrhythmias: A systematic review and meta-analysis of large populational studies.
Chye David M et al.
Heart rhythm
• 2026
BACKGROUND: Delta-9-tetrahydrocannabinol, a major component of cannabis, causes sympathetic stimulation and endothelial dysfunction. A recent American…
Preventing alcohol and cannabis-impaired driving among adolescents: Effects of a web-intervention in a driver education program.
Osilla Karen Chan et al.
Journal of substance use and addiction treatment
• 2026
INTRODUCTION: Adolescence is a critical period during which teens initiate and escalate substance use, as well as begin learning to drive. Limited res…
Cannabinoid-based interventions for behavioral outcomes in children and adolescents with autism spectrum disorder: A systematic review of safety and effectiveness.
Vasconcelos Quezia Damaris Jones Severino et al.
Progress in neuro-psychopharmacology & biological psychiatry
• 2026
BACKGROUND: Autism spectrum disorder (ASD) lacks effective options for core symptoms. Cannabinoids, especially cannabidiol (CBD) and combined CBD:Δ9-t…
Microvascular Effects of Endocannabinoid Signaling in Sepsis: A Mechanistic and Systematic Review.
Matias Emanuel F et al.
Microcirculation (New York, N.Y. : 1994)
• 2026
Microvascular dysfunction is a central determinant of organ failure in sepsis, reflecting early endothelial activation, increased permeability, and im…
Effects of cannabis edible advertising messages and warnings on product perceptions among US young adults.
Cui Yuxian et al.
Drug and alcohol dependence
• 2026
BACKGROUND: Despite increased popularity of cannabis edibles, limited research has assessed effects of warnings or advertising emphasizing different c…
Self-reported reasons for medical and nonmedical cannabis use in Australia: A cross-sectional analysis of the International Cannabis Policy Study 2023.
Dawson Danielle et al.
Drug and alcohol dependence
• 2026
INTRODUCTION: Australia’s medicinal cannabis framework has been increasingly used and commercialised. This study aimed to estimate the proportions of …
The role of hopelessness and depression in cannabis-induced first-episode psychosis: a 24-month prospective study.
Ricci Valerio et al.
Addictive behaviors
• 2026
Cannabis use is a recognized risk factor for psychosis, yet the psychological mechanisms mediating this relationship remain incompletely understood. T…
The Impact of Recreational Cannabis Legalization on Cannabis Use in U.S. Adults From 2016 to 2023: A Quasi-Experimental Study.
Hawkins Summer Sherburne et al.
American journal of preventive medicine
• 2026
INTRODUCTION: Although cannabis use has increased during a time of expanding cannabis legalization, there is limited evidence on how use has shifted i…
Cannabis legalization and early adolescent expectancies: Findings from the adolescent brain cognitive development study.
Ricklefs Colbey et al.
Drug and alcohol dependence
• 2026
PURPOSE: Cannabis legalization in the U.S. has introduced an ongoing public health challenge. Among adults, cannabis legalization is associated with i…
Social media use and health outcomes as moderated by rurality among sexual minority young adults.
Vogel Erin A et al.
The American journal on addictions
• 2026
BACKGROUND AND OBJECTIVES: Social media use may influence substance use and mental health symptoms differently for urban versus rural sexual minority …
The impact of recreational cannabis legalization on pediatric emergency department visits in British Columbia, Canada.
Xiao Melody et al.
Health promotion and chronic disease prevention in Canada : research, policy and practice
• 2026
INTRODUCTION: Canadian youth report some of the highest rates of cannabis use globally, raising concerns about child and youth poisonings from uninten…
Health Care Utilization and Developmental Delay Among Infants Exposed to Cannabis In Utero.
Raffa Brittany J et al.
Academic pediatrics
• 2026
OBJECTIVE: We examined the association between in utero cannabis exposure and well-child care (WCC) attendance, emergency department (ED) visits, and …
The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence.
Krzyżewska Anna et al.
British journal of pharmacology
• 2026
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes melli…
Cannabidiol synergizes with methotrexate to attenuate rheumatoid arthritis via STAT3/NF-κB signalling-mediated M1 macrophage polarization.
Xu Jiahe et al.
International immunopharmacology
• 2026
BACKGROUND: Methotrexate (MTX) is the anchor drug for rheumatoid arthritis (RA) treatment, but its clinical application is limited by dose-dependent a…
Effects of textual warnings and warning symbols on cannabis advertisements on product perceptions among US young adults.
Cui Yuxian et al.
Health education research
• 2026
States with legalized non-medical cannabis require different warnings on packages and advertisements; yet, studies examining effects of textual warnin…
Prepregnancy Care and Counseling: A Review.
Cooper Kylie M et al.
JAMA
• 2026
IMPORTANCE: Prepregnancy care and counseling optimize maternal health before conception to improve outcomes for mothers and infants. In the US, 66.4% …
A longitudinal DNA methylation atlas and its link to brain structure and mental health.
Chen Di et al.
Molecular psychiatry
• 2026
Epigenetic mechanisms are thought to contribute to neurodevelopmental vulnerability for psychiatric disorders, yet longitudinal evidence linking DNA m…
Longitudinal Relationships Between Cannabis and Tobacco Use and Symptom Severity in Individuals at Clinical High Risk for Psychosis.
Bai Yunong et al.
medRxiv : the preprint server for health sciences
• 2026
OBJECTIVE: Tobacco and cannabis are the most used substances among individuals at clinical high risk for psychosis (CHR-P), but it remains controversi…
Digest generated May 02, 2026 at 12:41 PM
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