Investigating Cannabidiol’s Impact on Glucose Metabolism in Obesity
This pilot study investigates cannabidiol glucose metabolism obesity effects in overweight adults. Short-term low-dose CBD supplementation showed no significant improvements in glucose tolerance. The study also found no changes in gut microbiome…
Endocannabinoid System Clinical Research: Pregnancy Alcohol Use Study
Prenatal alcohol exposure substance use frequently co-occurs with other substances, increasing developmental risks. Understanding these patterns is crucial for comprehensive screening during pregnancy. This research highlights the importance of…
Endocannabinoid System Research: Cannabis Clinical Trials Overview
Phase 3 cannabis clinical trials provide critical evidence on the effectiveness of full-spectrum cannabis extracts for chronic low back pain. This research highlights sustained pain relief and safety outcomes in large participant groups. The trials…
What 12 Weeks of Medicinal Cannabis Did for Endometriosis Pain
A 2026 medicinal cannabis endometriosis cohort study found a 31% reduction in pelvic pain and a 46% quality-of-life improvement over 12 weeks. Some patients discontinued opioids during the study. This research offers new clinical insights for…
What a Randomized Trial Found When Cannabis Went Head-to-Head With Lorazepam
A cannabis benzodiazepine alternative was tested in a Phase II randomized controlled trial comparing it directly to lorazepam for sleep improvement. The study found that the cannabis formulation matched lorazepam on the Pittsburgh Sleep Quality Index…
What the DOJ Cannabis Order Means for Patients and Clinicians
The medical cannabis Schedule III order is a major federal policy change, but it is not the same as new clinical proof. This Evidence Watch explains what the DOJ action may mean for research access, patient care, and regulated medical cannabis programs.…
Mechanistic Pathways Linking Cannabidiol, Hemp Seed Oil and Black Sesame Oil in Hyperarousal Insomnia: A Narrative Review.
This narrative review explores mechanistic pathways insomnia involving cannabidiol, hemp seed oil, and black sesame oil. It highlights how these compounds may modulate hyperarousal insomnia through multiple biological pathways. Understanding these…
Endocannabinoid Responses to Relief of Obstruction in Acute Injured Kidney: A Prospective Observational Study
The acute kidney injury endocannabinoid system plays a key role in regulating renal function during obstruction relief. This study tracks ECS responses in patients with acute renal colic. Findings highlight potential biomarkers for kidney injury and…
Characterizing Public Comments on Cannabis Rescheduling via Regulations.gov
This study analyzes cannabis rescheduling public comments submitted to Regulations.gov in 2024. Over 42,000 comments reveal diverse stakeholder perspectives on DEA's proposed Schedule III change. Understanding these comments helps clinicians anticipate…
Neuropathic Pain Severity Linked to Opioid Use in Adults with Traumatic SCI
This study investigates opioid use neuropathic pain spinal cord injury relationships in adults with traumatic SCI. Findings highlight employment as protective against opioid use. Multimodal approaches including cannabis are common in severe neuropathic…