Psychosocial Interventions for Substance Use Disorder: A Systematic Review of Therapeutic Approaches and Their Clinical Effectiveness.
This systematic review highlights substance use disorder treatment effectiveness through psychosocial interventions. Cognitive behavioral therapy and contingency management show consistent clinical benefits. The evidence guides clinicians in selecting…
Selective Personality-Targeted Intervention and the Escalation of Substance Use During Adolescence: A Secondary Analysis of A Cluster-Randomized Clinical Trial.
Personality-targeted cannabis prevention programs reduce adolescent cannabis use escalation by focusing on high-risk personality traits. This selective intervention approach offers a more precise prevention strategy than universal programs. It…
The effects of cannabidiol on sleep disturbances within a sample of high trait worriers: A double-blind, randomized placebo controlled trial.
This CBD sleep placebo trial found no significant benefit of cannabidiol over placebo for sleep disturbances in high trait worriers. The study challenges popular beliefs about CBD's effectiveness for sleep. It highlights the need for evidence-based…
Oral Cannabidiol in Treating TMJ Myofascial Pain: Clinical Trial Review
This clinical trial evaluated oral cannabidiol TMJ pain treatment in patients with temporomandibular myofascial pain disorder. Results showed oral CBD provided superior pain relief compared to placebo at one month. These findings highlight oral…
Cannabis-Based Medicines for Chronic Neuropathic Pain in Adults
The 2025 Cochrane review on cannabis-based medicines neuropathic pain provides the most rigorous analysis of cannabinoid effectiveness for chronic nerve pain. This systematic review update incorporates recent trial data to inform evidence-based clinical…
Medical marijuana for management of cancer pain: a narrative review.
A 2025 narrative review examines medical marijuana cancer pain management across 20 recent studies. It highlights ongoing knowledge gaps despite expanding legal access. The review consolidates current research trends on medical marijuana cancer pain…
Psychological and Psychosocial Interventions for Schizophrenia with Substance Use Disorders
This systematic review examines schizophrenia dual diagnosis treatment focusing on psychological and psychosocial interventions. It addresses a critical gap for patients with co-occurring substance use disorders. The research highlights the challenges…
Effects of Prescribed Medical Cannabis on Driving: Study Protocol Analysis
Australian researchers have developed a medical cannabis driving safety protocol to assess real-world driving performance in patients using prescribed THC. This two-phase trial aims to provide critical evidence on driving safety for medical cannabis…
Medical Cannabis for the Treatment of Peripheral Neuropathy due to Diabetes: A Systematic Review
This systematic review highlights cannabinoids diabetic neuropathy pain relief, showing significant benefits in three of four trials. THC-containing products demonstrated the strongest efficacy for diabetic nerve pain. These findings provide…
The efficacy and safety of cannabinoids for mental and substance use disorders: a systematic review and meta-analysis
A landmark cannabinoids mental health disorders systematic review published in The Lancet Psychiatry examines cannabinoids for mental health and substance use disorders. This comprehensive analysis addresses critical evidence gaps. The findings directly…