Regulating for Safety: Cannabidiol Dose in Food: A Review
While purified CBD is generally well-tolerated in clinical trials, the widespread availability of unregulated CBD-infused foods presents safety risks due.
A scoping review of the use of cannabidiol in psychiatric disorders
While cannabidiol (CBD) demonstrates a favorable safety profile and preliminary signals of efficacy in psychosis and anxiety.
Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies
Clinicians should consider the varying levels of evidence regarding the efficacy and safety of cannabis and cannabinoids when making treatment decisions.
Cannabinoid-based interventions for behavioral outcomes in children and adolescents with autism spectrum disorder: A systematic review of safety and effectiveness
While observational studies and one RCT suggest modest behavioral and social communication benefits from full-spectrum.
Cannabis and cannabidiol for postoperative pain management in orthopedic surgery: a scoping review
Current clinical evidence regarding the use of cannabinoids for postoperative pain in orthopedic surgery remains inconclusive due to significant trial.
Short-Term Cannabidiol with Δ-9-Tetrahydrocannabinol in Parkinson’s Disease: A Randomized Trial
A short randomised trial of a high-CBD, low-THC oral extract in 61 people with Parkinson's disease, a group who use cannabis often despite thin evidence.
Preoperative Oral Cannabidiol-Rich Cannabis Extract for Anxiety and Postoperative Pain After Endodontic Treatment
A double-blind trial testing whether a CBD-rich extract taken before a root canal reduced anxiety during the procedure or pain afterwards.
Oral Cannabis Extract for Chemotherapy-Induced Nausea and Vomiting: A Randomized, Placebo-Controlled Phase II/III Trial
A randomised trial in adults who were still being sick during chemotherapy despite already taking the standard anti-sickness medicines.
Tetrahydrocannabinol and Cannabidiol in Tourette Syndrome
A crossover trial in which 22 people with severe Tourette syndrome took both an oral THC/CBD oil and a placebo, six weeks each.
Medicinal Cannabis for Symptom Control in Advanced Cancer: A Randomised, Placebo-Controlled Trial of 1:1 THC and CBD
A placebo-controlled trial asking whether a 1:1 THC:CBD oil eased the overall symptom burden of advanced cancer beyond what palliative care already.
