Condition ARCHIVE

Parkinson's disease: research and patient questions

Physician-reviewed summaries of published studies and answered patient questions that name Parkinson's disease. Every study linked here carries a PubMed identifier that was checked against PubMed.

Verified NIH / PubMed 100% matched to primary citations

Graded Evidence Oxford CEBM clinical hierarchy

Plain-Language Insights Translated for patient understanding

All Research Studies 4 Pain 14 Adverse events 14 Cannabis use 13 Anxiety 13 Chronic pain 10 Pharmacokinetics 8 Cancer 8 Postoperative pain 7 Sleep 6 Inflammation 6

Cannabidiol-enriched cannabis extraction product in Parkinson’s disease: A randomized, double-blind, and placebo-controlled trial in Buriram Hospital

Anxiety Depression Parkinson's disease Cannabis CBD

This study involved patients diagnosed with Parkinson's disease who were given either a cannabidiol-enriched cannabis product or a placebo. The researchers aimed to see how effective the cannabis product was in improving symptoms of Parkinson's disease over an eight-week period. They measured various health outcomes to assess the impact of the treatment.

Key Findings: It helped. The cannabidiol-enriched cannabis product showed some effectiveness in improving symptoms of Parkinson's disease compared to the placebo. Patients reported better quality of life and symptom management.

Cannabis in Parkinson’s Disease - the patient’s perspective versus clinical trials: a systematic literature review

Parkinson's disease parkinson's disease

Currently, there is insufficient evidence to support the use of cannabinoids in treating Parkinson's Disease. Clinicians should consider larger randomized studies before recommending cannabinoid treatments to patients.

Key Findings: Only seven randomized trials on cannabinoids for PD were identified. Results did not support the efficacy of cannabinoids for motor symptoms. Insufficient data exists to recommend cannabinoids for PD patients.

Short-Term Cannabidiol with Δ-9-Tetrahydrocannabinol in Parkinson’s Disease: A Randomized Trial

Parkinson's disease CBD THC

A short randomised trial of a high-CBD, low-THC oral extract in 61 people with Parkinson's disease, a group who use cannabis often despite thin evidence.

Key Findings: Motor scores improved in both groups, and the difference between them was not significant. Sleep, thinking and daily activities slightly favoured placebo, and mild side effects were more common on the extract.

“Does cannabis help with tremor in Parkinson's disease?”

Parkinson's disease

For now, less than the enthusiasm suggests. In a randomised trial of a high-CBD, low-THC extract, motor scores improved in both the treatment and placebo groups, and the difference between them was not statistically significant. Sleep,...

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