Assessment of clinical outcomes in patients with post-traumatic stress disorder: analysis from the UK Medical Cannabis Registry
Further research is needed to establish the efficacy and safety of cannabis-based medicinal products in treating PTSD, as current evidence is limited.
Acute effects of MDMA and LSD co-administration in a double-blind placebo-controlled study in healthy participants
The co-administration of MDMA with LSD may prolong the subjective effects of LSD without altering their quality, which could be relevant in therapeutic settings. Caution is advised due to potential increases in blood pressure and heart rate.
Assessment of Orally Administered Δ9-Tetrahydrocannabinol When Coadministered With Cannabidiol on Δ9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics in Healthy Adults: A Randomized Clinical Trial
Clinicians should be cautious when prescribing CBD-dominant cannabis products, as they may produce stronger adverse effects than expected. Understanding cannabinoid interactions is crucial for safe therapeutic use.
A remote brief intervention plus social media messaging for cannabis use among emerging adults: A pilot randomized controlled trial in emergency department patients
Combining a brief motivational interviewing session with 4 weeks of tailored health coaching via a familiar social media platform (Snapchat) is a highly acceptable, engaging approach for reaching cannabis-using emerging adults in emergency care settings. While pilot results show promising improvements in readiness to change, larger definitive trials are needed to confirm long-term behavioral efficacy on consumption.
Acute pancreatitis as a rare adverse event among cannabis users: A systematic review
Cannabis-induced acute pancreatitis should be considered in young patients presenting with acute abdominal pain and elevated pancreatic enzymes in the absence of gallstones or heavy alcohol use. Cessation of cannabis along with conservative supportive care yields favorable recovery without mortality.