Cannabidiol in Developmental Epilepsy: Organoid-Guided Precision Medicine Across Critical Neurodevelopmental Windows
This review highlights cbd neurodevelopmental epilepsy precision medicine strategies using organoid models to guide treatment timing. It synthesizes evidence of CBD’s multiple mechanisms in developmental epilepsies. The research emphasizes the need for…
Endocannabinoid Responses to Relief of Obstruction in Acute Injured Kidney: A Prospective Study
The study investigates renal obstruction endocannabinoids and their role in acute kidney injury. It characterizes changes in circulating endocannabinoid levels before and after relief of obstruction. Understanding these responses may guide future…
Association of Cannabis Use Disorder Versus Other Substance Use Disorders With Psychiatric Conditions: A Propensity-Matched Retrospective Cohort Analysis.
This study examines the association cannabis use disorder psychiatric conditions compared to other substance use disorders. Researchers used a propensity-matched retrospective cohort analysis. The findings highlight differences in mental disorder risks…
Demographics, Methods, and Perceived Benefits of Cannabis Use in Cancer Patients
This study examines cannabis use among cancer patients, focusing on demographics, methods, and perceived benefits. It highlights key factors influencing use and patient experiences. Understanding cannabis use among cancer patients can inform clinical…
Magnetic Nanoparticles Anchored with Zeolites: Alternative Extraction Material
This study introduces magnetic nanoparticles zeolites extraction as a novel method for cannabinoid detection in urine samples. The technique offers a reliable alternative for dispersive magnetic solid-phase extraction. Magnetic nanoparticles anchored…
Cannabinoid Oral Mucosal Delivery: Approaches to Formulation, Fabrication, and Permeation Enhancement
Oral mucosal cannabinoid delivery offers a promising alternative to traditional oral routes by improving bioavailability and bypassing first-pass metabolism. This approach enhances the therapeutic potential of cannabinoids such as CBD and THC.…
Therapeutically Motivated Cannabis Use for Anxiety: Daily and Longitudinal Reductions Vary Between Flower and Edible Products.
This cannabis flower anxiety relief study found that flower products provide superior anxiety reduction compared to edibles. Therapeutically motivated users experienced different daily and longitudinal effects. Individual responses vary, highlighting the…
Head Down Tilt 15° to Increase Collateral Flow in Acute Ischemic Stroke: Rationale and Study Protocol
Head down tilt ischemic stroke therapy aims to increase collateral blood flow, a key factor in successful recanalization. This approach is being studied in acute ischemic stroke patients undergoing mechanical thrombectomy. The trial evaluates safety,…
The effect of hemp product consumption on blood fatty acid profiles and cardiovascular disease risk factors: results of a randomized, double-blind, crossover clinical trial.
A randomized crossover trial demonstrates that hemp seeds cardiovascular benefits include significant improvements in blood fatty acid profiles. This clinical research provides evidence-based support for hemp seeds as a nutritional intervention for…
Comparative Effectiveness, Safety, and Acceptability of Cannabis Use Disorder Treatments
Our primary aim was to conduct a network meta-analysis on the comparative effectiveness cannabis use disorder treatments. We evaluated both pharmacological and psychosocial interventions. This study highlights safety and acceptability outcomes for these…