CAN-PACT: Advancing Psychedelic-Assisted Therapy in Oncology Supportive Care
The CAN-PACT initiative focuses on psychedelic-assisted therapy oncology supportive care for cancer patients experiencing demoralization syndrome. This multi-phase program emphasizes training, safety, and research infrastructure. It aims to establish…
Reductions in Cigarette and Cannabis Use During Alcohol Treatment
This study reveals polysubstance use alcohol treatment patterns with significant cigarette reductions and a biphasic cannabis use trend. Participants in an alcohol use disorder trial showed early cannabis decreases followed by later increases.…
Efficacy and Safety of Cannabinoids for Neuropsychiatric Symptoms of Dementia: A Systematic Review with Meta-analysis.
This systematic review evaluates the efficacy and safety of cannabinoids for neuropsychiatric symptoms in dementia. Neuropsychiatric symptoms are common in dementia and pose significant challenges. Cannabinoids offer a promising treatment option for…
An Adapted Brief Negotiation Interview for Alcohol and Cannabis Use Among Assault-Injured Emerging Adults
This study outlines a brief cannabis intervention emergency department protocol tailored for assault-injured emerging adults. It adapts a brief negotiation interview to address co-occurring alcohol and cannabis use. The protocol focuses on intervention…
Randomized and Blind Evaluation of the Efficacy of a Full-Spectrum Oral Cannabis Extract
This randomized clinical trial demonstrates that full-spectrum cannabis osteoarthritis pain relief is significant compared to placebo. The study provides controlled evidence supporting cannabinoid analgesic effects in degenerative joint disease. These…
IBS Clinical Care Gaps and Future Therapeutics via Peripheral Visceral Afferent Modulation
Peripheral visceral afferent modulation is a promising but unproven approach for IBS pain management. This review highlights the unmet need for safe and effective pain treatment in IBS. Translation from rodent models to human therapeutics remains a…
Detection of Δ9-Tetrahydrocannabinol Impairment Using Resting-State Functional Near-Infrared Spectroscopy: A Randomized Clinical Trial.
This randomized trial demonstrates that THC impairment detection via functional near-infrared spectroscopy is more accurate than field sobriety tests. The neuroimaging method offers an objective approach to cannabis impairment testing. These findings…
Reducing Severe Breathlessness with Dronabinol in Severe COPD Patients
A new randomized crossover trial will investigate whether dronabinol COPD breathlessness treatment can help patients with severe symptoms. This protocol review examines the study design and clinical context for cannabis medicine in respiratory care. The…
Does oral cannabidiol oil in adjunct to pain medications help reduce pain and improve locomotion in dogs with osteoarthritis?
This systematic review evaluates veterinary CBD osteoarthritis pain management, finding weak evidence that CBD oil may modestly reduce pain in dogs. The review synthesizes data from four clinical trials assessing CBD as an adjunct to conventional pain…
Insights Into Cannabis and Cannabinoids: Chemical Properties, Legal Perspectives, and Therapeutic Applications.
Cannabinoids chemical properties play a crucial role in the therapeutic applications of cannabis. This review explores the chemical compounds and legal perspectives surrounding cannabinoids. Understanding these properties helps inform clinical practice…