Comparative Pharmacokinetics and Safety of Cannabidiol in a Powder Formulation, CBtru
This study on cbd powder formulation pharmacokinetics reveals comparable bioavailability to traditional oil-based CBD products. It highlights formulation-dependent food effects on absorption in healthy adults. While bioequivalence is established,…
Higher THC Concentration Medicinal Cannabis Products Efficacy and Safety Considerations: A Rapid Review.
A rapid review of 15 studies examining higher THC medicinal cannabis efficacy found therapeutic benefits for chronic pain and PTSD. The review also confirmed increased risk of cognitive and psychiatric adverse effects. This evidence provides important…
Analgesic Effect of Cannabinoids for Fibromyalgia: A Systematic Review and Meta-Analysis
This meta-analysis highlights cannabinoid analgesia fibromyalgia benefits with statistically significant pain reduction. Fibromyalgia patients often face inadequate relief from conventional therapies. Cannabinoid analgesia fibromyalgia offers a promising…
Psychosocial Interventions for Substance Use Disorder: A Systematic Review of Therapeutic Approaches and Their Clinical Effectiveness.
This systematic review highlights substance use disorder treatment effectiveness through psychosocial interventions. Cognitive behavioral therapy and contingency management show consistent clinical benefits. The evidence guides clinicians in selecting…
Selective Personality-Targeted Intervention and the Escalation of Substance Use During Adolescence: A Secondary Analysis of A Cluster-Randomized Clinical Trial.
Personality-targeted cannabis prevention programs reduce adolescent cannabis use escalation by focusing on high-risk personality traits. This selective intervention approach offers a more precise prevention strategy than universal programs. It…
The effects of cannabidiol on sleep disturbances within a sample of high trait worriers: A double-blind, randomized placebo controlled trial.
This CBD sleep placebo trial found no significant benefit of cannabidiol over placebo for sleep disturbances in high trait worriers. The study challenges popular beliefs about CBD's effectiveness for sleep. It highlights the need for evidence-based…
Oral Cannabidiol in Treating TMJ Myofascial Pain: Clinical Trial Review
This clinical trial evaluated oral cannabidiol TMJ pain treatment in patients with temporomandibular myofascial pain disorder. Results showed oral CBD provided superior pain relief compared to placebo at one month. These findings highlight oral…
Cannabis-Based Medicines for Chronic Neuropathic Pain in Adults
The 2025 Cochrane review on cannabis-based medicines neuropathic pain provides the most rigorous analysis of cannabinoid effectiveness for chronic nerve pain. This systematic review update incorporates recent trial data to inform evidence-based clinical…
Medical marijuana for management of cancer pain: a narrative review.
A 2025 narrative review examines medical marijuana cancer pain management across 20 recent studies. It highlights ongoing knowledge gaps despite expanding legal access. The review consolidates current research trends on medical marijuana cancer pain…
Psychological and Psychosocial Interventions for Schizophrenia with Substance Use Disorders
This systematic review examines schizophrenia dual diagnosis treatment focusing on psychological and psychosocial interventions. It addresses a critical gap for patients with co-occurring substance use disorders. The research highlights the challenges…