Associations of Cannabis and Tobacco Use with Suicide Attempt, Suicide Death, and Overdose Death Among Veterans Prescribed Opioid Analgesics.
A large longitudinal study of over 900,000 Veterans examined cannabis suicide risk veterans prescribed opioids, revealing different associations with suicide outcomes compared to tobacco use. The research provides new insights into substance use patterns…
Impact of Preoperative Marijuana Use on Functional Recovery and Complications After Spinopelvic Fusion in Adult Spinal Deformity.
With the rising prevalence of marijuana use and increasing rates of complex spinal deformity surgeries, understanding the impact of cannabis on perioperative...
Patient perspectives on non‑traumatic painful upper‑extremity conditions, co-occurring risky substance use, and an integrated web-based mind-body intervention addressing both conditions.
Recent qualitative research examining upper extremity pain and substance use management reveals patients commonly use alcohol, cannabis, and tobacco for symptom relief but lack awareness of pain-substance interactions. The study provides insights for…
Ketamine addiction following a single sub-anaesthetic ketamine treatment for acute suicidality in a psychiatrically multimorbid patient: case report.
A 25-year-old patient developed severe ketamine addiction after single dose treatment for suicidality, highlighting ketamine addiction after single dose treatment risks in vulnerable populations. This case emphasizes the importance of comprehensive…
Cognitive performance and subjective effects the morning after last use of smoked cannabis by adults who use cannabis frequently: An observational study.
A controlled observational study found no cognitive impairment in regular cannabis users 12-15 hours after smoking, with important implications for understanding cannabis cognitive effects next day. This research provides evidence that cognitive function…
Early-life exposure to Cannabidiol: Safety assessment of a chronic exposure in Caenorhabditis elegans.
Recent toxicology research examining CBD safety in early development reveals dose-dependent safety profiles with oxidative stress mechanisms. This preclinical work provides important insights for pediatric CBD applications while highlighting the need for…
Cannabinoid-based interventions for behavioral outcomes in children and adolescents with autism spectrum disorder: A systematic review of safety and effectiveness.
A comprehensive systematic review examining cannabinoids for autism in children and adolescents reveals promising response rates of 49% versus 21% placebo, though evidence quality limitations require careful clinical interpretation. The review…
Efficacy of high-definition transcranial direct current stimulation on craving in substance use disorders: a systematic review and meta-analysis.
A systematic review and meta-analysis demonstrates that HD-tDCS for substance use disorder craving shows efficacy across multiple substances. This brain stimulation technique offers a non-invasive approach to managing one of addiction's core symptoms,…
CBD reduces chronic pain in new randomized controlled trial
CBD pain research reveals clinically significant reductions in chronic pain in a new randomized controlled trial. This study provides evidence supporting CBD as a potential adjunctive therapy. Clinicians can now reference this CBD pain research when…
Real-Time and Long-Term Effects of Medical Marijuana on Older Adults: Study Protocol
The study on medical marijuana effects older adults addresses critical gaps in understanding both real-time and long-term impacts. Older adults are the fastest-growing group using medical marijuana, primarily for chronic pain. This prospective cohort…