Safety and Efficacy of MAOIs in Patients Using Psychoactive Substances
Monoamine oxidase inhibitors drug interactions safety is crucial for patients using psychoactive substances. This review highlights the relative safety of MAOIs in such patients. Careful monitoring and individualized assessment are essential for optimal…
Cannabis effects on cardiovascular health: Evidence, gaps, and future directions
Cannabis cardiovascular safety concerns are increasingly important as use expands globally. Current evidence shows mixed results but a stronger link to atrial arrhythmias. This review highlights critical gaps in knowledge and the need for cautious…
Investigational Drugs in PTSD: Emerging Clinical Evidence
The endocannabinoid system and PTSD clinical evidence reveal promising investigational drugs targeting neurobiological pathways. PTSD remains challenging with limited FDA-approved options. Emerging treatments like ketamine and cannabinoids offer hope for…
Randomised Controlled Trial Evidence on Medicinal Cannabis for Treatment of Mental Health and Substance Use Disorders: A Scoping Review.
This scoping review synthesizes randomised controlled trial evidence medicinal cannabis for treating mental health and substance use disorders. The review addresses previous limitations in study design and quality. It provides clinicians with a clearer…
Therapeutic Use of Cannabis and Cannabinoids: A Comprehensive Review
This review covers therapeutic cannabinoid applications with a focus on FDA-approved uses. It highlights evidence supporting cannabinoids for nausea, appetite, and seizure disorders. Approximately 27% of adults report medical cannabis use, underscoring…
Cannabis use in chronic pancreatitis: A narrative review.
Cannabis use chronic pancreatitis is explored in this narrative review focusing on pain management challenges. Evidence suggests potential opioid-sparing effects but remains limited. Further research is needed to clarify cannabis' role in chronic…
Exploring CBD as a Prophylactic Agent Against Glioblastoma Growth
This CBD glioblastoma preclinical study examines cannabidiol's potential to reduce tumor growth in glioblastoma. The research shows prolonged CBD exposure may modulate immune and tumor markers. While promising, these findings are preliminary and require…
Effect of Cannabigerol on Sleep and Quality of Life in Veterans: A Decentralized, Randomized, Placebo-Controlled Trial
This cannabigerol sleep study veterans trial evaluated oral CBG for sleep quality in veterans with sleep disturbances. The study found a favorable safety profile but inconclusive efficacy results. It highlights the need for further research on CBG's…
The Canadian Network for Psychedelic-Assisted Cancer Therapy (CAN-PACT): A Multi-Phase Program Overview
The CAN-PACT program focuses on psychedelic-assisted therapy cancer patients to address demoralization syndrome. This multi-phase initiative aims to improve supportive care for advanced cancer patients. It establishes clinical infrastructure and training…
Potency-Related Effects of Smoked Cannabis on Driving Performance
This randomized trial investigates cannabis driving impairment effects linked to smoked cannabis potency. The study provides evidence on how THC levels affect simulated driving performance. These findings inform clinical counseling and patient safety…