Osteoarthritis is a common inflammatory and degenerative joint disease characterized by associated chronic pain, often ensuing to diminished quality of life….
Safety and Efficacy of Monoamine Oxidase Inhibitors in Patients Who Use Psychoactive Substances: Potential Drug Interactions and Substance Use Disorder Treatment Data.
Monoamine oxidase inhibitors (MAOIs) remain an important option for patients with treatment-resistant depression (TRD) and other psychiatric conditions, desp…
Cannabis effects on cardiovascular health: Current evidence, gaps in knowledge, and future research directions.
As cannabis use accelerates globally with expanding legalization and availability of high-potency formulations, concerns regarding its cardiovascular safety …
Investigational drugs in PTSD.
Post-traumatic stress disorder (PTSD) remains one of psychiatry’s most challenging disorders, common, disabling, and biologically complex. Despite decades of…
Randomised Controlled Trial Evidence on Medicinal Cannabis for Treatment of Mental Health and Substance Use Disorders: A Scoping Review.
With shifting perceptions about the therapeutic potential of cannabis and evolving regulatory frameworks, global prescribing of medicinal cannabis is increas…
Therapeutic Use of Cannabis and Cannabinoids: A Review.
Approximately 27% of adults in the US and Canada report having ever used cannabis for medical purposes. An estimated 10.5% of the US population reports using…
Cannabis use in chronic pancreatitis: A narrative review.
Chronic pain is a debilitating complication of chronic pancreatitis for which treatment options are limited. The goal of this narrative review was to summari…
Cannabidiol as a Prophylactic Agent Against Glioblastoma Growth: A Preclinical Investigation.
Glioblastoma (GBM) remains one of the most lethal brain tumors, with current therapies offering limited benefits and high relapse rates. This study presents …
Effect of Cannabigerol on Sleep and Quality of Life in Veterans: A Decentralized, Randomized, Placebo-Controlled Trial.
This decentralized, randomized, triple-blind, placebo-controlled study evaluated efficacy and safety of oral cannabigerol (CBG) in Veterans with sleep issues…
The CAnadian Network for Psychedelic-Assisted Cancer Therapy (CAN-PACT): A Multi-Phase Program Overview.
The CAnadian Network for Psychedelic-Assisted Cancer Therapy (CAN-PACT) was launched in 2025 to address urgent gaps in supportive care for Canadians with can…