The efficacy of oral cannabidiol (CBD) for the management of myofascial pain disorder (MPD) of the temporomandibular region remains understudied. Therefore, …
The Limits of Averages: A Framework for Contextual Effectiveness in Palliative Care Medicinal Cannabis Research.
This article introduces a framework of contextual effectiveness to reconcile the persistent gap between patients’ positive experiences with treatments and ne…
Analgesic Effect of Cannabinoids for Fibromyalgia: A Systematic Review and Meta-Analysis.
Fibromyalgia is a kind of complex chronic pain syndrome that exerts a profound impact on patients’ lives. Current pharmacological treatments for fibromyalgia…
Efficacy and Safety of Cannabinoids for Neuropsychiatric Symptoms of Dementia: A Systematic Review with Meta-analysis.
Neuropsychiatric symptoms (NPS) are highly prevalent in persons with dementia and have been associated with adverse health outcomes. Neuropsychiatric symptom…
Comparative Pharmacokinetics and Safety of Cannabidiol in a Powder Formulation, CBtru
Emerging evidence indicates that cannabidiol (CBD) may offer meaningful therapeutic benefits across neurological, pain, and psychiatric disorders. Cannabidio…
CBD for anxiety in Brain Tumors patients
CBD for anxiety in brain tumor patients is an appealing idea, but this early-terminated randomized crossover trial did not show benefit over placebo. The study also found no clear improvement in depressive symptoms, despite using high-purity oral CBD at 600 mg/day. Because the sample was small and underpowered, the fairest takeaway is cautious skepticism rather than sweeping certainty.
Does oral cannabidiol oil in adjunct to pain medications help reduce pain and improve locomotion in dogs with osteoarthritis?
In dogs with osteoarthritis (OA), does the oral supplementation of cannabidiol (CBD) oil, compared to conventional treatment alone, improve treatment outcome…
Muscular Dystrophy Muscle Preservation: A Comparative Systematic Review of Exercise and Cannabidiol (CBD) Interventions.
Muscular dystrophy comprises a heterogeneous group of inherited neuromuscular disorders characterized by progressive muscle degeneration, weakness, and funct…
CBD for Sleep Disturbances: Trial Review
This page reviews a 2026 randomized placebo-controlled trial of CBD for sleep disturbances in adults with elevated trait worry. It explains what was measured, what was found, what was not proved, and why readers should be careful not to overstate a modest dose-comparison signal as definitive efficacy. Relevant entities and search concepts include cannabidiol, CBD isolate, sleep quality, sleep disturbance, placebo response, randomized controlled trial, sleep support, cannabis medicine, evidence review, dosing, and anxiety-related sleep complaints.
Efficacy of high-definition transcranial direct current stimulation on craving in substance use disorders: a systematic review and meta-analysis.
Substance use disorder is a chronic, relapsing illness, and craving plays an important factor in relapse. High-definition transcranial direct current stimula…