Evidence-based Therapist Guided Introduction to Online Heavy Cannabis Use Treatment in Canadian Adults: A Randomized Controlled Trial (RCT)
Many people who engage in heavy cannabis use do not seek treatment, and those who do face barriers like wait times and costs. Therapist guided cannabis treatment delivered online can reduce these barriers. This study evaluates a Canadian online program…
Safety and Efficacy of Monoamine Oxidase Inhibitors in Patients Using Psychoactive Substances
Monoamine oxidase inhibitors drug interactions are critical to understand for patients using psychoactive substances. This review highlights safety considerations and treatment data. MAOIs remain important for treatment-resistant psychiatric conditions…
Cannabis Use Among Individuals Treated with Medication for Opioid Use Disorder: Correlates, Patterns, and Motivations for Use.
Cannabis use is prevalent among patients receiving medication for opioid use disorder (MOUD). However, little is known about factors associated with frequent...
Phase 1 Open-Label Pilot Trial of H4 Deep Repetitive Transcranial Magnetic Stimulation for Adults With Moderate-to-Severe Cannabis Use Disorder.
Cannabis use disorder (CUD) is a significant public health problem and no medical treatments have received regulatory approval to date. Deep repetitive trans...
Cannabidiol in Anorexia Nervosa: A Double-Blind Randomized Placebo Controlled Pilot Study
This cannabidiol anorexia nervosa study evaluates safety, pharmacokinetics, and symptom change in patients with anorexia nervosa. The randomized controlled trial used a double-blind design to assess cannabidiol effects. Results suggest cannabidiol is…
Head Down Tilt 15° to Increase Collateral Flow in Acute Ischemic Stroke: Rationale and Study Protocol
Head down tilt ischemic stroke therapy aims to increase collateral blood flow, a key factor in successful recanalization. This approach is being studied in acute ischemic stroke patients undergoing mechanical thrombectomy. The trial evaluates safety,…
Efficacy and Safety of Cannabinoids for Neuropsychiatric Symptoms of Dementia: A Systematic Review with Meta-analysis.
Neuropsychiatric symptoms (NPS) are highly prevalent in persons with dementia and have been associated with adverse health outcomes. Neuropsychiatric symptom...
Insights Into Cannabis and Cannabinoids: Chemical Properties, Legal Perspectives, and Therapeutic Applications.
Cannabinoids chemical properties play a crucial role in the therapeutic applications of cannabis. This review explores the chemical compounds and legal perspectives surrounding cannabinoids. Understanding these properties helps inform clinical practice…
Plasma Cannabinoid Pharmacokinetics After Vaporized Cannabis Inhalation
This study investigates cannabinoid pharmacokinetics vaporized cannabis, focusing on how cannabidiol (CBD) influences THC plasma concentrations. It provides critical data on absorption and metabolism after inhalation. Understanding these interactions is…
Oral Cannabidiol in the Treatment of Myofascial Pain Disorder of the Temporomandibular Region: A Placebo-Controlled Randomized Clinical Trial.
The oral cannabidiol myofascial pain disorder trial investigates CBD's efficacy for temporomandibular pain. This placebo-controlled randomized clinical trial evaluates pain reduction and jaw function. Results could inform future treatment options for…