Potency-related effects of smoked cannabis on simulated driving performance: a randomized, controlled crossover trial.
CED Clinical Relevance #86High Clinical Relevance Strong evidence or policy relevance with direct clinical implications. 🔬 Evidence Watch | CED Clinic Driving SafetyThcImpairmentDosingRct…
Cannabinol for Acute Treatment of Insomnia Disorder in a Randomized Placebo-Controlled Crossover Trial.
Insomnia disorder is harmful and requires novel treatments. Cannabinol, an oxidative by-product of Δ9-tetrahydrocannabinol, is claimed to be a hypnotic, but ...
Reductions in cigarette and cannabis use during a randomized clinical trial for alcohol use disorder.
Alcohol, tobacco, and cannabis are the most frequently used psychoactive substances in the United States and are commonly used concurrently. This study analy...
Efficacy and safety of cannabidiol oil in psoriasis: a randomized, double-blind, placebo-controlled trial.
The management of psoriasis presents challenges, prompting many patients to seek alternative treatments. Cannabidiol (CBD) has demonstrated potential antioxi...
Racial diversity in cannabis use disorder research: A systematic review.
Several groups of people of color have a higher prevalence and more severe cases of cannabis use disorder (CUD) compared to White people. They also endure un...
A Randomized, Open-Label Trial to Assess Feasibility and Tolerability of Topical Cannabis Balms for the Treatment of Aromatase Inhibitor-Associated Musculoskeletal Syndrome (AIMSS).
Aromatase inhibitors (AIs) are commonly used for postmenopausal women with hormone receptor-positive breast cancer. Nearly two-thirds of women on AIs have ar...
Vaporized cannabis versus placebo for acute migraine: A randomized, double-blind, placebo-controlled crossover trial.
To assess the efficacy of cannabis for the treatment of acute migraine. Preclinical and retrospective studies suggest cannabinoids may be effective in migrai...
Detection of Δ9-Tetrahydrocannabinol Impairment Using Resting-State Functional Near-Infrared Spectroscopy: A Randomized Clinical Trial.
The primary psychoactive compound in cannabis, ∆9-tetrahydrocannabinol (THC) induces intoxication and functional impairment, raising safety concerns in drivi...
Selective Personality-Targeted Intervention and the Escalation of Substance Use During Adolescence: A Secondary Analysis of A Cluster-Randomized Clinical Trial.
Substance use is a leading cause of burden of disease worldwide. Selective prevention programs can help reduce the development of problematic substance use a...
Medical marijuana for management of cancer pain: a narrative review.
The increasing legalization of medical marijuana in the United States (US) has spurred ongoing interest in its clinical application for the management of can...