Biobio Sentinel: Two years of illicit drug surveillance in South-Central Chile.
A two-year wastewater cannabis surveillance study in Chile revealed dramatic population-level drug consumption changes, with cannabis use declining over 90% while cocaine consumption increased tenfold. This environmental monitoring approach provides…
Neurologic Complications of Drug and Alcohol Use.
A comprehensive clinical review identifies emerging neurologic complications across substance classes, with particular attention to potential cannabis-stroke associations. The review provides neurologists with systematic approaches for recognizing…
Cannabis legalization and law enforcement drug seizures: a state-level analysis of cannabis policy effects on cannabis seizures in the United States, 2010-2023.
A comprehensive 13-year analysis reveals that cannabis legalization reduces drug seizures significantly, with recreational programs showing greater impact than medical-only policies. This research demonstrates how cannabis legalization reduces drug…
Self-reported reasons for medical and nonmedical cannabis use in Australia: A cross-sectional analysis of the International Cannabis Policy Study 2023.
A 2023 Australian survey found that cannabis users frequently report dual medical-recreational motives rather than distinct categories. This cross-sectional analysis of 3,042 adults reveals that australian medical cannabis use patterns are more nuanced…
Association of Multimodal Cannabis Use with Adverse Events among Adolescents and Young Adults.
The ways cannabis is consumed, or modes of use, have increased and diversified in recent years, especially among young people. Associations of multimodal can...
Pilot Cross-Sectional Study Assessing the Correlation between Marijuana Use and Rheumatoid Arthritis and Systemic Lupus Erythematosus Exacerbations.
Cannabis use is increasing among patients with autoimmune rheumatic diseases, often for symptom relief; however, its impact on disease activity remains uncle...
Implementation of a Standardized Management Algorithm for Cannabis Hyperemesis Syndrome in a Pediatric Emergency Department.
Cannabis hyperemesis syndrome (CHS) is an increasingly common cause of pediatric emergency department (ED) visits, yet management pathways remain understudie...
The role of cannabinoid ligands in neurodegenerative diseases: emerging anti-inflammatory, immunomodulation and disease-modifying perspectives.
Neurodegenerative diseases (NDs) constitute a growing global health burden driven by population aging and remain without disease-modifying therapies. Althoug...
Analytical Challenges and Emerging Detection Strategies of Synthetic Cannabinoids in Horse Doping Control.
Synthetic cannabinoids (SCs) were originally synthesized to advance the understanding of the endocannabinoid system, facilitate disease research, and support...
Aryl-Cyclohexanone as a Potential CB2 Agonist: In Vitro and In Silico Evidence in Inflammatory Modulation.
Inflammation is an evolutionarily conserved adaptive process essential for host defense against harmful stimuli, aimed at restoring homeostasis. However, exa...
