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Cannabis-based medicines for chronic neuropathic pain in adults.
Estimates of chronic neuropathic pain affect 6% to 10% of adults. Cannabis-based medicines for chronic neuropathic pain offer a potential treatment option when conventional therapies fail. Current evidence suggests modest benefits with important safety…
Medical Marijuana for Management of Cancer Pain: A Narrative Review
This narrative review examines cannabis efficacy cancer pain management based on recent studies. It highlights the potential role of cannabinoids in oncology pain relief. Clinicians should consider cannabis as part of a multimodal approach to cancer pain.
Endocannabinoid System & Adolescent Cannabis Use Risk
Internalising symptoms cannabis use risk adolescents is a key factor in adolescent cannabis uptake. Adolescents with anxiety and depression symptoms show increased cannabis use over time. This evidence supports targeted interventions for mental health to…
Effects of Prescribed Medical Cannabis and Alcohol on Real-World Driving Performance (CAN-TRACK): Study Protocol
The effects of prescribed medical cannabis on driving are under investigation in the CAN-TRACK study. This research evaluates real-world driving performance in patients using therapeutic cannabis. Understanding these effects is crucial for informed road…
Adolescent Cannabis Use and Mental Health: Clinical Evidence
Adolescent cannabis use psychotic disorder risk guide highlights the increased risk of psychotic and other psychiatric disorders in teens. Clinical evidence shows these risks are significant and clinically diagnosed. Families and clinicians should be…
Research on Cannabis Use and Pre-Trauma Insomnia
Pre-trauma insomnia cannabis use is linked to increased risk of substance use after trauma. Research shows insomnia symptoms before trauma predict cannabis use in the following weeks. Clinicians should screen for sleep disturbances to identify substance…
Cannabinoid Clinical Trials: Sleep & EEG Insomnia Study
This pilot trial examined acute effects oral cannabinoids sleep in adults with insomnia disorder. A single dose of THC and CBD reduced total sleep time compared to placebo. High-density EEG provided detailed sleep architecture data.
Cannabinoids for Mental & Substance Use Disorders: Evidence
Current evidence on cannabinoids for substance use disorders shows limited and inconsistent benefits. Safety concerns remain a consistent finding across clinical trials. The efficacy of cannabinoids for mental and substance use disorders remains…
Cannabis Oil Did Not Meaningfully Reduce Pain in Nerve-Injury Patients, Rigorous Trial Finds
This cannabis brachial plexus pain RCT found cannabis-based medicine did not improve pain by a clinically important margin. The study advises against adding cannabis oil to standard pain treatment for traumatic brachial plexus injury. Sleep quality…
Australian Trial to Test Medicinal Cannabis Against Chemotherapy’s Gut Side Effects
Cannabinoid clinical trials for chemotherapy mucositis are underway to evaluate CBD/THC's potential in preventing gastrointestinal side effects. This phase II trial tests sublingual wafers in adults receiving mucotoxic chemotherapy. Results are pending,…