Lifestyle and Behavioral Enhancements of Sleep: A Review
Sleep hygiene CBT-I is a cornerstone of behavioral interventions for sleep disorders, offering evidence-based lifestyle enhancements. This review highlights the importance of non-pharmacological therapies in improving sleep quality sustainably.…
Nationwide Outcomes of Cardiac Surgery in Patients with Cannabis Use Disorder
This study evaluates cannabis use disorder cardiac surgery outcomes using a nationwide database. Findings show no increased in-hospital morbidity or mortality linked to cannabis use disorder. The research highlights the importance of assessing…
Anesthesia Needs for Cannabis Users During Wisdom Tooth Surgery
Propofol dosing cannabis users require during third molar removal under intravenous anesthesia may be higher than nonusers. This study highlights the need for tailored anesthetic management in cannabis-exposed patients. Understanding propofol dosing…
Activation of Cannabinoid Receptor 1 Enhances Wound Healing by Promoting the Proliferative Phase
Activation cannabinoid receptor type 1 plays a crucial role in wound healing by promoting the proliferative phase. This process involves increased fibroblast proliferation and enhanced extracellular matrix synthesis. Understanding this mechanism may…
Targeting Mechanosensitive CB1 with Isoflavone Prodrugs to Reduce Atherosclerosis
Atherosclerotic endothelial dysfunction is a key factor in cardiovascular disease progression. Targeting mechanosensitive cannabinoid receptor 1 with isoflavone prodrugs offers a novel approach to reduce vascular inflammation. This strategy may improve…
Management of Opioid Withdrawal Syndrome and Opioid Dependence Treatment
Opioid withdrawal management is critical in cases involving synthetic opioid contamination such as protonitazene. This case report highlights the need for adjusted buprenorphine dosing. Effective opioid dependence treatment requires awareness of these…
Cannabis-Based Spray Shown Feasible and Safe for Alzheimer’s Agitation in UK Care Homes
The nabiximols Alzheimer agitation trial demonstrated that administering this cannabis-based spray is feasible and safe for patients in UK care homes. Despite challenges, the study showed perfect adherence and no adverse drug reactions. These results…
Cannabis Medicines Cause Dose-Dependent Side Effects in Older Adults, Meta-Analysis Finds
Dose-dependent side effects cannabinoids cause include dizziness, dry mouth, and coordination difficulties in older adults. This 2024 meta-analysis highlights the importance of cautious dosing. Understanding these risks helps clinicians manage…
Older Adults Prescribed Cannabis in UK Show Self-Reported Well-Being Gains, But Study Design Cannot Confirm Treatment Caused Improvement
The older adults cannabis registry study from the UK shows self-reported well-being improvements after prescribed cannabis use. However, the study design lacks a control group, so treatment effects cannot be confirmed. These findings highlight the need…
A Geriatrics Cannabis Clinic Shows Feasibility—But Not Yet Effectiveness
This report highlights geriatric cannabis clinic feasibility in a medically complex older adult population. It reveals an average of 4.6 drug interactions per patient, emphasizing pharmacological risks. The study underscores the need for structured…