Unraveling Lennox-Gastaut Syndrome: Molecular Pathogenesis and Therapeutic Strategies
Lennox-Gastaut syndrome treatment challenges arise from its complex network dysfunction and drug-resistant seizures. Precision medicine approaches targeting molecular pathways offer new hope. CBD has shown efficacy as adjunctive therapy for this severe…
Precision Prediction of PTSD Symptom Surges Using Machine Learning
Machine learning PTSD prediction offers a promising approach to forecast symptom surges using real-time daily data. This pilot study integrates supervised learning to enhance dynamic symptom tracking. The findings highlight potential for early…
Factors Associated with Disposable vs Non-Disposable E-Cigarette Use in Adults
Disposable electronic cigarette use has rapidly increased among adults in the U.S. and Israel. This study identifies key factors influencing preferences between disposable and non-disposable devices. Understanding these patterns is essential for…
Medical Cannabis in Older Adults: Promising Interest, Thin Evidence
Medical cannabis safety older adults is a critical concern due to limited evidence and unique risks in this population. Current studies mostly exclude adults over 60, leaving a gap in clinical guidance. Careful individualized decision-making is essential…
Older Adults on Medical Cannabis Face Doubled Intoxication Risk When Co-Prescribed Narrow Therapeutic Index Drugs
Medical cannabis drug interactions older adults face are a growing concern, especially with narrow therapeutic index drugs. A large Ontario cohort study found a 2.61-fold increase in intoxication risk among older adults co-prescribed cannabis and these…
Common But Manageable: What a 58-Trial Meta-Analysis Reveals About Cannabis Medicine Side Effects in Older Adults
Cannabinoid adverse events older adults are dose-dependent and mostly manageable according to a 58-trial meta-analysis. THC-containing medicines increase common side effects like dizziness and dry mouth in older adults. Serious adverse events do not…
Older Adults Using Prescribed Cannabis Report Well-Being Improvements, But Causal Claims Remain Unsupported
Medical cannabis older adults registry data reveal notable well-being improvements among elderly patients using prescribed cannabis. This observational study highlights trends but cannot confirm causality. The findings inform clinical understanding while…
Cannabis Use Linked to Higher Blood Clot Risk in Older Trauma Patients
This study investigates thromboembolic risk geriatric trauma patients face when testing positive for THC. Findings show significantly higher rates of deep vein thrombosis and pulmonary embolism among cannabis users. These results highlight the importance…
Three Preliminary Studies on Cannabis, Social Isolation, and Dementia
Geriatric psychiatry cannabis research reveals early signals but no firm conclusions on cannabinoids' effects in older adults. Studies highlight social isolation and dementia contexts. Controlled evidence remains insufficient for clinical guidance.
Older Adults Using Cannabis for Sleep Rely More on THC and Use It More Frequently, Small Clinic Survey Finds
Cannabis use patterns older adults targeting sleep show a higher frequency and preference for THC-containing products. This small clinic survey highlights distinct behaviors in geriatric cannabis users. Understanding these patterns is crucial for…
