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Cannabis for MS Spasticity: A Systematic Review With Critically Unreliable Pooled Estimates
This cannabis MS spasticity review examines nine trials with 2,544 patients but finds critically unreliable pooled estimates due to extreme heterogeneity. The meta-analysis reports numerically implausible effect sizes and suspected publication bias.…
Brief Online Mindfulness Training Does Not Reduce Cannabis Use in Adults with Cannabis Use Disorder
A brief online mindfulness program was tested for its effect on cannabis use disorder. The study found no significant reduction in cannabis use frequency or craving. These findings highlight the challenges of brief digital mindfulness interventions for…
Small Pilot Trial Tests Medicinal Cannabis for Teen Tourette Syndrome—Finds Protocol Feasible, Efficacy Questions Remain
The medicinal cannabis tourette syndrome adolescents pilot trial demonstrates that a rigorous study protocol is feasible and acceptable to families. While the trial cannot confirm efficacy, it lays groundwork for future research. A fully powered study is…
Cannabis Does Not Consistently Change Sleep Architecture, Meta-Analysis Finds
A 2025 meta-analysis finds cannabis withdrawal sleep disruption is consistent, while cannabis does not reliably change sleep architecture. Polysomnographic evidence shows no clear benefit or harm on most sleep parameters. These findings highlight the…
Therapeutic Effects of a Sesquiterpene-Rich Cannabis Essential Oil on Neuroinflammation
This study highlights the effects of a sesquiterpene-rich essential oil cannabis on neuroinflammation and symptom relief in multiple sclerosis models. The essential oil acts through CB2 receptor pathways to provide neuroprotection. These findings suggest…
Associations of Prenatal Cannabis Exposure and Neonatal Brain Development in the HBCD Cohort
Prenatal cannabis exposure neonatal brain development is increasingly studied due to rising cannabis use during pregnancy. This study examines how timing and frequency of exposure affect early brain structure. Understanding these associations is crucial…
Research Digest: 5 Recent Studies – March 25, 2026
This research digest presents recent studies on the real-time and long-term effects of medical marijuana. The focus is on older adults and how medical marijuana impacts cognitive and physical health. These findings provide valuable insights into medical…
Bridging Reward and Resilience: Endocannabinoid System in Depression
The endocannabinoid system depression connection is key to understanding exercise's antidepressant effects. Moderate aerobic exercise activates CB1 receptors, enhancing stress resilience. This mechanism offers a promising framework for managing major…
Association of Multimodal Cannabis Use with Adverse Events among Adolescents and Young Adults.
Multimodal cannabis consumption risks are rising among adolescents and young adults. This study reveals that using multiple cannabis methods correlates with increased adverse events. Understanding these risks is crucial for effective harm reduction…
Associations of Cannabis and Tobacco Use with Suicide Attempt, Suicide Death, and Overdose Death Among Veterans Prescribed Opioid Analgesics
This cannabis suicide risk veterans prescribed opioids study examines associations between cannabis and tobacco use with suicide attempt, suicide death, and overdose death among veterans. The longitudinal cohort study followed over 920,000 veterans…