Medical Cannabis for Chronic Pain: Promise, Pharmacology, and Persistent Gaps
This 2025 medical cannabis chronic pain review examines the pharmacology and clinical evidence for cannabinoids in pain management. While promising, significant gaps remain in standardized dosing and long-term safety data. The review highlights the need…
Acute and Long-Term Psychiatric Consequences of Synthetic Cannabinoids and Related Novel Psychoactive Substances: A Systematic Review
This systematic review examines psychiatric consequences synthetic cannabinoids cause, highlighting both acute and long-term effects. Synthetic cannabinoids present significant psychiatric risks distinct from natural cannabis. Understanding these…
Comparative Effectiveness, Safety, and Acceptability of Cannabis Use Disorder Treatments
This cannabis use disorder treatment research analyzes pharmacological and psychosocial interventions through a network meta-analysis. It highlights the limited evidence for medication effectiveness and supports psychosocial approaches. The study guides…
Cannabinoids in Children: Clinical Evidence Review
The cannabinoids pediatric safety evidence review covers clinical research spanning 276 studies on cannabinoid use in children. This evolving evidence base reflects growing interest and cautious interpretation due to limited long-term safety data.…
Development of a Decision Aid to Support Shared Decision-Making on Cannabis Use for Arthritis: Protocol for a Multiphase Study.
This study focuses on shared decision-making cannabis arthritis to develop a decision aid supporting patients and clinicians. Arthritis patients often seek cannabis when conventional treatments provide partial relief. The decision aid aims to facilitate…
Cannabis and Sleep Review, Read Carefully
This paper is a systematic review and meta-analysis on recreational cannabis use and sleep in the general population. It brings together observational and experimental studies and finds that poorer sleep outcomes appear more often in observational data…
Survey of 47 Trials Maps Cannabinoid Research in Neurology—But Evidence Gaps Remain Large
This review maps cannabinoid clinical trials neurology, highlighting 47 completed studies focused on conditions such as Multiple Sclerosis and Fibromyalgia. It reveals significant evidence gaps due to non-standardized protocols and outcome measures. The…
First Systematic Typology of Cannabis Harm Reduction Strategies Maps a Fragmented Field
This 2024 scoping review presents a cannabis harm reduction typology that classifies legal, organizational, and health-related strategies. It highlights the fragmented field and the lack of effectiveness data. The typology provides a foundation for…
Medical Cannabis Evidence Map: Broad Promise, Variable Proof
The 2024 medical cannabis evidence map synthesizes 194 systematic reviews across 71 health outcomes, focusing on high-quality evidence. It highlights positive or potentially positive effects for pain, seizures, anxiety, and more. This map guides…
Cannabinoids Show Modest Promise for Cancer-Related Appetite Loss in Older Adults, But Evidence Remains Thin
Cannabinoid receptor type 1 activation plays a role in appetite regulation for older adults with cancer-related anorexia. Current evidence shows modest benefits but remains limited and inconclusive. Further research is needed to establish clinical…