Cannabis Use Disorder Strongly Linked to Major Depression, New Review Finds
✦ New CED Clinical Relevance #78 Strong Clinical Relevance High-quality evidence with meaningful patient or clinical significance. Mental HealthResearchTHCCannabis Use DisorderDepressionSafetyNeurology Why This Matters Clinicians treating patients…
Clinical Evidence on GLP-1 Receptor Agonists and Hair Loss
GLP-1 receptor agonist hair loss is a recognized adverse effect linked to rapid weight loss and metabolic changes. Clinical evidence shows this hair loss is typically reversible and related to telogen effluvium. Understanding this helps clinicians…
GLP-1 Receptor Agonists: Cardiovascular and Metabolic Clinical Evidence
GLP-1 receptor agonists cardiovascular and metabolic evidence highlights their dual therapeutic benefits in managing type 2 diabetes and obesity. These agents improve glycemic control and reduce cardiovascular risk beyond weight loss. Understanding this…
Efficacy of pharmacological treatments for Dravet syndrome: Systematic review and network …
✦ New CED Clinical Relevance #85 Strong Clinical Relevance High-quality evidence with meaningful patient or clinical significance. ResearchNeurologyCBDPediatricsSafety Why This Matters This systematic review and network meta-analysis provides…
Cannabis Medicines Show Modest Promise for Nerve Pain, But Evidence Remains Inconclusive
Cannabis medicines neuropathic pain evidence suggests potential benefits for nerve pain relief. However, study limitations like small samples and short durations hinder firm conclusions. More rigorous trials are needed to clarify efficacy and safety.
From Analgesia to Synaptic Remodeling: A Systematic Review of Acetaminophen’s Neuromodulatory Effects.
Neuro-related disorders will be rising globally. Current treatments have numerous limitations that can impair patients' quality of life. One of the key thera...
Development of a Decision Aid to Support Shared Decision-Making on Cannabis Use for Arthritis: Protocol for a Multiphase Study.
Conventional treatments have been frequently reported to offer partial relief for some individuals managing arthritis pain and related symptoms, leading many to consider cannabis. The development of a decision aid cannabis arthritis tool aims to support…
Prevalence of Schizophrenia Spectrum and Bipolar Disorder in Cannabis Induced Psychosis Patients
Distinguishing cannabis induced psychosis prevalence from primary psychiatric disorders is challenging and clinically important. This systematic review and meta-analysis examines the prevalence of schizophrenia spectrum and bipolar disorder among these…
Comparative Effectiveness, Safety, and Acceptability of Cannabis Use Disorder Treatments
Our primary aim was to conduct a network meta-analysis on the comparative effectiveness cannabis use disorder treatments. We evaluated both pharmacological and psychosocial interventions. This study highlights safety and acceptability outcomes for these…
The efficacy and safety of cannabinoids for mental and substance use disorders: a systematic review and meta-analysis
A landmark cannabinoids mental health disorders systematic review published in The Lancet Psychiatry examines cannabinoids for mental health and substance use disorders. This comprehensive analysis addresses critical evidence gaps. The findings directly…