Development of a Decision Aid to Support Shared Decision-Making on Cannabis Use for Arthritis: Protocol for a Multiphase Study.
Conventional treatments have been frequently reported to offer partial relief for some individuals managing arthritis pain and related symptoms, leading many to consider cannabis. The development of a decision aid cannabis arthritis tool aims to support…
Prevalence of Schizophrenia Spectrum and Bipolar Disorder in Cannabis Induced Psychosis Patients
Distinguishing cannabis induced psychosis prevalence from primary psychiatric disorders is challenging and clinically important. This systematic review and meta-analysis examines the prevalence of schizophrenia spectrum and bipolar disorder among these…
Comparative Effectiveness, Safety, and Acceptability of Cannabis Use Disorder Treatments
Our primary aim was to conduct a network meta-analysis on the comparative effectiveness cannabis use disorder treatments. We evaluated both pharmacological and psychosocial interventions. This study highlights safety and acceptability outcomes for these…
The efficacy and safety of cannabinoids for mental and substance use disorders: a systematic review and meta-analysis
A landmark cannabinoids mental health disorders systematic review published in The Lancet Psychiatry examines cannabinoids for mental health and substance use disorders. This comprehensive analysis addresses critical evidence gaps. The findings directly…
GLP-1 Receptor Agonist Cardiovascular Evidence: Meta-Analysis
This GLP-1 receptor agonist cardiovascular meta-analysis synthesizes data from major trials demonstrating reduced cardiovascular events. The evidence supports GLP-1 receptor agonists as cardioprotective agents beyond weight loss. Clinicians can use this…
GLP-1 Weight Loss Cardiovascular Evidence: Meta-Analysis Review
Intragastric balloon therapy obesity is a meaningful treatment option for patients not ready for surgery or pharmacotherapy. This therapy offers short-term weight reduction comparable to semaglutide 2.4 mg weekly. Understanding this evidence helps…
Strategies for Muscle Preservation During GLP-1 Therapy
Muscle preservation during GLP-1 receptor agonist therapy is critical to avoid excessive lean mass loss. This page discusses strategies to maintain muscle while benefiting from GLP-1 treatments. Clinicians should emphasize resistance training and…
Medical Cannabis for Orthopaedic Pain: Promising Signal, Weak Evidence Base
Medical cannabis orthopedic pain is a growing area of patient interest despite limited high-quality evidence. This review highlights promising signals for musculoskeletal conditions but notes weak study designs. Clinicians should consider cannabis as…
Tirzepatide vs Semaglutide: Weight & Muscle Loss Outcomes
This article reviews tirzepatide vs semaglutide weight loss clinical evidence, highlighting differences in muscle loss outcomes. Tirzepatide shows greater total weight loss but may increase lean mass depletion compared to semaglutide. Understanding these…
Comparing Clinical Evidence of GLP-1 Receptor Agonists
GLP-1 receptor agonist clinical evidence drug comparisons reveal important sex-based differences in obesity outcomes. Understanding these differences helps tailor weight management strategies. Genetic factors also influence individual responses to GLP-1…
