Using Machine Learning to Identify Unique Predictors of Alcohol and Cannabis Impaired Driving
Machine learning impaired driving predictors reveal new risk factors for alcohol and cannabis use among young adults. This study highlights unique insights beyond traditional methods. Understanding these predictors can enhance clinical screening and…
Therapeutically Motivated Cannabis Use for Anxiety: Daily and Longitudinal Reductions Vary Between Flower and Edible Products.
This study explores cannabinoid pharmacology anxiety and its impact on therapeutic cannabis use for anxiety. It compares daily and longitudinal anxiety reductions between flower and edible cannabis products. Understanding these effects is essential for…
The Endocannabinoid System in Obsessive-Compulsive Disorder: A Scoping Review.
About 40% of individuals with obsessive-compulsive disorder do not respond to current treatments. This review focuses on endocannabinoid system OCD research, emphasizing preclinical evidence. Understanding ECS modulation may inform future therapeutic…
The role of cannabis-based medicinal products (CBMPs) in managing osteoarthritis symptoms: a scoping review of current evidence and future directions.
This review critically evaluates cbd topical pain safety in managing osteoarthritis symptoms. It highlights clinical evidence supporting cannabis-based medicinal products for symptom relief. The review also discusses future directions for research and…
Taurine attenuates lipid accumulation via the eCB-CB1 axis: evidence from adipose metabolomics in HFD-fed mice and 3D adipocyte spheroids.
Taurine lipid accumulation modulation via the eCB-CB1 axis offers new insights into obesity management. This study highlights taurine's role in adipose tissue metabolism. Findings suggest potential pathways for metabolic disorder interventions.
Cannabinoids and cognition in Parkinson’s disease: Insights from animal models and emerging clinical evidence.
Cannabinoids and cognition in Parkinson's disease are increasingly studied due to the endocannabinoid system's role in neural circuits affected by PD. Animal models show promising neuroprotective and cognition-preserving effects of cannabinoids. However,…
Enhancing Endocannabinoid System for Residual Disease in MS
This clinical study endocannabinoid system approach addresses residual disease in relapse-free multiple sclerosis patients. High-efficacy therapies reduce relapses but symptoms persist. Enhancing the endocannabinoid system offers new treatment insights.
Targeting the LPI/GPR55 Axis in MAFLD and MASH: Novel Insights, Therapeutic Strategies and Future Directions.
The LPI GPR55 receptor axis plays a crucial role in metabolic dysfunction-associated fatty liver disease (MAFLD). This pathway contributes to liver fat accumulation, inflammation, and fibrosis. Understanding this axis offers novel insights into potential…
Cannabinoids in Combination with Conventional Breast Cancer Therapies: Mechanistic Insights and the Gap to Clinical Translation.
This review highlights cannabinoid anti-tumor effects breast cancer research and its potential to enhance conventional therapies. It emphasizes the gap between preclinical findings and clinical translation. Understanding these effects is crucial for…
Pharmacokinetic and Pharmacodynamic Properties of Cannabigerol in Male Mice
This study investigates the pharmacokinetic properties of cannabigerol in male mice, highlighting its brain penetration and metabolite accumulation. Findings reveal unexpected anxiogenic effects at peak brain concentrations. Understanding these…
