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Endocannabinoid System & Alcohol Use Disorder: Evidence from Preclinical & Human Studies
The endocannabinoid system alcohol use disorder evidence highlights its role in regulating reward, stress, and emotional processing. Preclinical studies show cannabinoid receptor modulators reduce alcohol intake. However, human trials have shown…
The effect of daily aerobic cycling exercise on cannabis withdrawal: An inpatient randomised controlled trial.
A randomized controlled trial of 46 adults found that daily aerobic cycling exercise significantly reduced cannabis withdrawal symptom severity during the critical first week of abstinence. This represents the first controlled evidence that aerobic…
The wake of addiction: Pharmacological strategies for sleep disturbances in stimulant use disorders, a systematic review.
A systematic review of sleep disturbances in stimulant use disorders identifies 18 studies examining pharmacological interventions for sleep problems in cocaine and methamphetamine addiction. While the evidence base remains limited, this review…
Efficacy of high-definition transcranial direct current stimulation on craving in substance use disorders: a systematic review and meta-analysis.
A systematic review and meta-analysis demonstrates that HD-tDCS for substance use disorder craving shows efficacy across multiple substances. This brain stimulation technique offers a non-invasive approach to managing one of addiction's core symptoms,…
Evidence-based Therapist Guided Introduction to Online Heavy Cannabis Use Treatment in Canadian Adults: A Randomized Controlled Trial (RCT)
Many people who engage in heavy cannabis use do not seek treatment, and those who do face barriers like wait times and costs. Therapist guided cannabis treatment delivered online can reduce these barriers. This study evaluates a Canadian online program…
Analyzing Trump’s Psychedelic Executive Order: Clinical Insights
This article provides a focused psychedelic executive order analysis highlighting its clinical impact. It examines how regulatory changes influence research and patient treatment access. Clinicians are encouraged to review policy details to understand…
Efficacy of high-definition transcranial direct current stimulation on craving in substance use disorders: a systematic review and meta-analysis.
High-definition transcranial direct current stimulation is a promising noninvasive method for reducing craving in substance use disorders. This systematic review and meta-analysis evaluates its efficacy. The focus on craving highlights its potential role…
Ask the Expert: How Is Cannabis Use Disorder Diagnosed and Treated?
Cannabis use disorder diagnosis criteria are essential for identifying this underrecognized condition. Treatment options focus on behavioral therapies and managing withdrawal symptoms. Understanding these criteria helps clinicians provide better care.
GLP-1 Drugs Offer Real Hope for People With Pain or Addiction
GLP-1 receptor agonists pain management is gaining attention for its potential to reduce chronic pain and aid addiction treatment. These drugs, originally for diabetes, show promise beyond metabolic effects. Emerging evidence suggests they may offer…
Effectiveness of Cognitive Behavioral Therapy for Harmful Cannabis Use
Cognitive behavioral therapy cannabis use disorder treatment shows moderate effectiveness in reducing cannabis use frequency and related problems. This therapy helps patients develop coping strategies and modify thought patterns. Understanding its…