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Cannabinoids for Cancer Pain: New Review Questions the Opioid-Sparing Claim
A 2026 systematic review and meta-analysis found cannabinoids did not reliably reduce opioid use in controlled cancer-pain studies. This challenges the opioid-sparing cancer pain claim often made in clinical discussions. The findings suggest cannabinoids…
Cannabis Use and Poor Mental Health: What the New U.S. Trends Show
The cannabis mental health trends 2023 reveal an increase in poor mental health days among adults reporting cannabis use. This large U.S. survey highlights the need for better mental health screening. However, it does not prove cannabis caused the trend.
High-Dose CBD for Spinal Cord Injury Nerve Pain
The high-dose cannabidiol neuropathic pain trial showed modest reduction in spinal cord injury nerve pain. This randomized crossover study tested doses up to 800 mg daily. Results indicate a credible analgesic signal but do not support unsupervised…
The DEA’s June 29 Hearing Explained: What Full Cannabis Rescheduling Would Mean for Medical Patients
A federal DEA hearing beginning June 29, 2026 will determine whether all cannabis -- not just state-licensed medical marijuana -- moves from Schedule I to Schedule III. Here's what already changed on April 28, what the hearing is actually deciding, and…
General Purpose AI Models Beat Clinical AI Tools in Medical Study
General purpose AI models have been shown to outperform specialized clinical AI tools in a comprehensive medical study. The research evaluated multiple AI systems using real physician queries and found general purpose AI models consistently superior.…
Autism, Schizophrenia, and Shared Biology: Why This Review Is Not Really a Cannabis Paper
A June 2026 review described shared pathways across autism spectrum disorder and schizophrenia, including endocannabinoid dysfunction. Its value is conceptual rather than cannabinoid-specific or treatment-directing.
What Survives After the Information Is Gone?
Framework preservation is the effort to preserve a useful way of thinking, not just the information that originally introduced it. This essay explores how AI Projects can help capture questions, assumptions, examples, cautions, and reasoning habits that…
A Cannabis-Based Medicine Goes Head-to-Head With Lorazepam for Sleep
A cannabis insomnia randomized trial published in 2026 compared a traditional cannabis-based herbal medicine with lorazepam for chronic insomnia. Both groups experienced substantial improvements in sleep quality, quality of life, and stress scores over…
Cannabis Oil for Fibromyalgia: New RCT Results Explained
A new Australian randomized, double-blind, placebo-controlled pilot trial found that a nightly 1:1 THC:CBD cannabis oil produced clinically meaningful pain relief in 70% of fibromyalgia patients, with large effect sizes for sleep quality and fibromyalgia…
Why THC Feels More Predictable When Inhaled Than Eaten
Inhaled vs oral THC effects were compared in a systematic review and dose-response meta-analysis of 41 placebo-controlled trials involving 1,020 participants. Researchers found that inhaled THC showed a measurable relationship between dose and subjective…