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Endocannabinoids and Polyunsaturated Fatty Acids in Early Schizophrenia: Changes Under Antipsychotics and Treatment Response
The endocannabinoid system schizophrenia alterations are evident in early stages of the disorder. This study highlights changes in polyunsaturated fatty acids and endocannabinoids before and after antipsychotic treatment. Understanding these biochemical…
Reasons for Cannabis Use Among Adults with Disabilities: Insights from the 2023-2024 Survey
Cannabis use among adults with disabilities is notably higher than in the general population. The 2023-2024 National Survey on Health and Disabilities reveals key reasons for this trend. Understanding cannabis use among adults with disabilities is…
Is cannabis legalization associated with treatment completion? A study of pregnant women admitted for cannabis use in substance use treatment facilities, 2020-2022.
Pregnant women cannabis treatment completion is a critical measure in understanding recovery success amid evolving legalization. This study analyzes treatment completion rates for pregnant women admitted for cannabis use disorder from 2020 to 2022.…
The quality and scope of health information on online drug platforms: a topic modelling and expert evaluation study of a Polish-language forum.
This study evaluates health information quality online drug platforms, focusing on user-generated content from a Polish-language forum. It reveals how cannabis users discuss symptom relief and inflammation management. Understanding this quality is…
Therapeutic Potential and Pharmacological Mechanisms of Cannabinoids in Alleviating Chemotherapy-Induced Organ Toxicity
Cannabinoids chemotherapy organ protection research highlights their potential to reduce organ toxicities caused by chemotherapy. These include cardiotoxicity, nephrotoxicity, hepatotoxicity, and neurotoxicity. Understanding pharmacological mechanisms is…
Unraveling Endocannabinoid Signaling Pathways in Cisplatin-Induced Ototoxicity
Cisplatin-induced ototoxicity is a detrimental side effect of chemotherapy leading to hearing loss, for which no treatments are currently available. This study reveals the presence of endocannabinoid signaling pathways in auditory hair cells affected by…
Standardizing Recreational Cannabis Excise Tax Rates in the United States: New Retail Price-Based Measurements by Product Category
Standardized cannabis excise tax rates reveal significant variation across product categories and states. Understanding these tax burdens is crucial for clinicians advising patients on cost-effective cannabis therapy. This analysis highlights the impact…
Prevalence, Patterns, and Correlates of Cannabis-Cigarette Co-Use: Findings From a Multi-State Rapid-Response Survey in the U.S., 2023-2024.
Cannabis cigarette co-use prevalence is significant among adults in high-tobacco states, with nearly half of cigarette smokers also using cannabis. This pattern suggests important clinical considerations for dual substance use. Understanding cannabis…
Understanding Delta-8-THC Vaping Pharmacokinetics
This clinical study examines delta-8-thc vaping pharmacokinetics in humans, addressing a key knowledge gap. Findings suggest vaped delta-8-thc may be more potent than smoked cannabis. Understanding these effects is crucial for patient safety and clinical…
Investigating the Synergistic Effect of Cannabis Extract PHEC-66 and Chemotherapy on Melanoma
This study explores cannabis chemotherapy interactions melanoma by testing the cannabis extract PHEC-66 with chemotherapy agents on melanoma cells. Results show potential additive and antagonistic effects depending on the drug. Understanding cannabis…