Cannabinoid Clinical Trials: Mental Health & Substance Use
Cannabinoids mental health studies highlight that current evidence does not firmly establish cannabinoids as effective primary treatments for most mental health or substance use disorders. Adverse effects were commonly reported, emphasizing clinical…
Association of Cannabis Use Disorder Versus Other Substance Use Disorders With Psychiatric Conditions: A Propensity-Matched Retrospective Cohort Analysis
This study examines the cannabis use disorder psychiatric risk profile compared to other substance use disorders. Findings indicate lower rates of schizophrenia, depression, and psychotic disorders in cannabis users. These insights inform clinical risk…
Cannabinoids, Autophagy, and Alzheimer’s Disease, What This Review Explores and What It Still Leaves Unproven
This 2026 review explores how cannabinoids might influence autophagy pathways relevant to Alzheimer’s disease. Its value is mainly mechanistic and hypothesis-building, with some discussion of early clinical and preclinical signals. It does not prove that…
Acute Toxicity of ADB-CHMINACA – Case Series with Pronounced CNS Symptoms
This report presents a series of 16 patients with acute toxicity of ADB-CHMINACA confirmed by analytical testing. Patients exhibited pronounced central nervous system symptoms including panic attacks and seizures. The study highlights the dangers of…
Attitudes, Beliefs and Willingness to Prescribe Medical Cannabis Among Public Medical Practitioners in Malaysia
This survey highlights physician attitudes medical cannabis Malaysia, showing 65% support among public medical practitioners. Pain management, particularly cancer pain, is the leading indication for prescribing willingness. These findings provide…
Cannabis Pharmacokinetics Review: THC, CBD, Dosing
This paper is a broad evidence review of human pharmacokinetic studies on THC and CBD. It helps clarify how route, formulation, food, sex, drug interactions, and patient factors can meaningfully change absorption and exposure. Its main limitation is that…
Development of a Decision Aid to Support Shared Decision-Making on Cannabis Use for Arthritis: Protocol for a Multiphase Study.
This study focuses on shared decision-making cannabis arthritis to develop a decision aid supporting patients and clinicians. Arthritis patients often seek cannabis when conventional treatments provide partial relief. The decision aid aims to facilitate…
Cannabis and Sleep Review, Read Carefully
This paper is a systematic review and meta-analysis on recreational cannabis use and sleep in the general population. It brings together observational and experimental studies and finds that poorer sleep outcomes appear more often in observational data…
Innovative Aptamer-Based Liquid Sensing Display for Label-Free Detection
This study introduces an aptamer-based liquid sensing display for label-free THC detection. The technology integrates with smartphones for rapid, point-of-care analysis. Aptamer-based liquid sensing display offers a novel approach to illicit substance…
Letter by Wu et al Regarding Article, “G Protein-Coupled Receptor Kinase 3 Exacerbates Diabetic Heart Injuries Through Direct Phosphorylation of Cannabinoid Receptor 2 in Humans and Mice”.
This letter discusses cannabinoid receptor 2 phosphorylation and its role in diabetic heart injury. The phosphorylation by GRK3 may impair CB2 receptor function in diabetes. Understanding cannabinoid receptor 2 phosphorylation is key to future diabetic…
