The Endocannabinoid System Modulating Levels of Consciousness, Emotions and Likely Dream Contents
The endocannabinoid system sleep-wake cycle plays a crucial role in regulating consciousness and emotions. This system, including receptors like CB1, influences sleep and wakefulness. Research suggests it may also modulate dream contents and related…
Anti-Invasion Effects of Cannabinoids on Breast Cancer Stem Cells
Recent research highlights cannabinoids breast cancer stem cells as key in reducing tumor invasiveness. Synthetic cannabinoids targeting CB1 receptors show promise in inhibiting cancer stem cell migration. These findings suggest cannabinoids breast…
The CB1R rs2023239 Receptor Gene Variant and Nicotine Reinforcement in Smokers
Tobacco smoking is a leading cause of preventable death, yet only one-third of those who try can successfully quit smoking. The CB1 receptor gene variant nicotine significantly affects nicotine reinforcement among smokers. This finding highlights the…
Using Measured Cannabinoid Metabolites in Urine to Differentiate Marijuana Use
The cannabinoid metabolites urine test measures THC and CBD metabolites to differentiate marijuana use from commercial CBD product consumption. Current marijuana drug tests may misidentify consistent CBD users as marijuana users. This test improves…
Understanding the Antiepileptic Mechanisms of CBD in Epilepsy
CBD antiepileptic mechanisms involve modulation of neuronal receptors and adenosine signaling to reduce seizures. Research highlights its effects on GPR55, TRPV1, and adenosine pathways. These mechanisms support CBD's role in epilepsy management.
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
Cannabidiol as a novel inhibitor of Id-1 gene expression shows promise in reducing the invasiveness of aggressive breast cancer cells. This focus on cannabidiol as a novel inhibitor of Id-1 gene expression highlights its potential therapeutic role.…
Safety and Tolerability of Cannabidiol in Parkinson Disease: An Open Label, Dose-Escalation Study
Parkinson disease patients often seek alternative treatments like cannabidiol. This study investigates the safety and tolerability of cannabidiol in Parkinson disease. Results show mild adverse events and potential symptom improvement.
Self-reported Illicit Drug Use Among Norwegian University and College Students: Association with Age, Gender, and Geography
Self-reported illicit drug use among Norwegian university students has shown notable trends by age, gender, and geography. The study highlights increased drug use prevalence from 2014 to 2018. These findings emphasize the importance of addressing student…
Stress, Emotional Intelligence and the Intention to Use Cannabis in Spanish Adolescence: Influence of COVID-19 confinement
The study on stress and cannabis use adolescents during COVID-19 confinement reveals increased stress levels but no immediate rise in cannabis use intention. Emotional intelligence was found to protect against cannabis consumption among teens. These…
Tetrahydrocannabinol-Rich Extracts Enhance Brain Glucose Consumption and Metabolic Modulation
Tetrahydrocannabinol brain glucose consumption plays a crucial role in modulating metabolic complications linked to neurodegenerative diseases. THC-rich extracts from Cannabis Sativa L. improve glucose uptake and reduce oxidative stress in brain tissue.…