Pain Improved, Cravings Did Not: A Buprenorphine Study
Medical cannabis with buprenorphine was associated with modest improvements in pain, sleep, and quality of life over three months in adults with opioid use disorder and chronic pain. Opioid-positive urine screens declined numerically, but the change was…
GLP‑1 Receptor Agonist Treatment and Health Outcomes in Methadone‑Treated Patien
GLP-1 receptor agonists significantly reduced myocardial infarctions, opioid overdoses, and suicidal ideation in methadone-treated OUD patients with T2D.
What a Target Trial Emulation Reveals About GLP-1 Safety in Patients With Opiate Use Disorder
This large target trial emulation evaluated GLP-1 safety in opioid use disorder using national claims data. Investigators found no increased risk across ten gastrointestinal, psychiatric, respiratory, and renal outcomes. The findings provide important…
Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms
A groundbreaking clinical trial is investigating stress induced opioid misuse mechanisms in chronic back pain patients by examining how acute stress modulates endogenous opioid and endocannabinoid systems. This research could identify biomarkers that…
Opioid Use Disorder Among Cervical Fusion Inpatients: Trends, Complications, and Resource Use in a Retrospective National Inpatient Sample Analysis, 2016-2022.
A large retrospective study reveals that opioid use disorder affects 3.4% of cervical fusion surgery patients, with these individuals experiencing significantly longer hospital stays and higher complication rates. This population-level data provides…
Cannabis Use Among Individuals Treated with Medication for Opioid Use Disorder: Correlates, Patterns, and Motivations for Use
Cannabis use among individuals on MOUD is common and linked to various clinical factors. This study examines patterns and motivations for cannabis use in this population. Understanding these factors can inform clinical practice and patient care.
Study: CBD’s Role in Opioid Use Disorder and Relapse Prevention
CBD opioid use disorder research highlights its potential to reduce heroin-seeking behavior by reversing brain changes linked to relapse. This study suggests CBD may complement existing treatments for opioid addiction. Understanding these neurobiological…
Exploring Cannabis in Opioid Addiction Treatment – Canadian Affairs
Cannabis opioid use disorder treatment is an emerging area of clinical interest amid the ongoing overdose crisis. Current evidence suggests cannabis may help with opioid withdrawal symptoms and craving reduction. However, more robust clinical trials are…
Trump Plans To Sign Executive Order On The Psychedelic Ibogaine As Soon As This Week …
Ibogaine opioid use disorder treatment is gaining attention with Trump's upcoming executive order. This psychedelic shows promise but carries cardiac safety risks. Clinical oversight is essential for safe access and effective policy.
Evaluating Cannabis Exposure and Its Effect on Substance Use Trajectories
This study evaluates cannabis exposure substance use trajectories among people using unregulated drugs during the fentanyl crisis. Understanding these trajectories is vital for clinical risk assessment. The findings could shape harm reduction and…