CB2 Receptor Levels Predict Blood-Brain Barrier Repair in HIV Models
medical cannabis research: In vitro research demonstrates that cannabinoid receptor 2 activation protects blood-brain barrier integrity in high-expression endothelial cell lines while failing to help or worsening damage in low-expression cell lines. It…
Evaluating Targeted School Interventions for Adolescent Substance Use Risk
medical cannabis research: The Canadian Underage Substance Use Prevention trial evaluated PreVenture, a personality-targeted school intervention designed to curb adolescent alcohol, cannabis, and drug use, while adapting its protocol following…
Evaluating Palliative Pain Strategies in Older Adults Across Clinical Evidence
medical cannabis research: This scoping review maps 117 studies on palliative pain management in older adults, revealing heavy research emphasis on cancer and opioids while highlighting significant gaps in non-cancer populations and high-quality data. It…
Meditation and Mind Altering Substances in Real World Practice
medical cannabis research: Naturalistic survey data show alcohol and cannabis are paired with meditation far more frequently than psychedelics, with unexpected differences in reported well-being across distinct substance groups. It keeps the evidence…
Alcohol Does Not Halt Tobacco Cessation Gains in HIV Care
medical cannabis research: A clinical trial analysis shows that unhealthy alcohol use reduces clinic attendance among people living with HIV, yet pharmacist-led nicotine replacement and contingency management maintain smoking cessation efficacy across…
Evaluating Cannabidiol for Pain: Where Clinical Trials Diverge from Hype
medical cannabis research: High-quality randomized clinical trials consistently show pure cannabidiol monotherapy fails to outperform placebo for acute and chronic pain conditions, contrasting sharply with widespread consumer marketing and preclinical…
Adolescent Cannabis Use Alters Brain Reward Pathways and Decision Outcomes
medical cannabis research: Brain imaging reveals that regular cannabis exposure starting before age eighteen blunts striatal responses during reward anticipation while heightening sensitivity to loss. These neurological shifts correlate with measurable…
Cannabis Use and Early Psychiatric Rehospitalization in Young Adults With Bipolar or Psychotic Disorders
medical cannabis research: A 200-patient historical cohort links cannabis use at psychiatric admission with higher early readmission risk, especially during the first month after discharge. It keeps the evidence readable for patients and clinicians. The…
THC and Social Behavior in Rodents Shows Dose, Timing, and Model Dependence
medical cannabis research: A systematic review of 49 rodent studies found THC often reduced normal social behavior, while low doses sometimes improved deficits in selected impairment models, with reporting quality limiting confidence. It keeps the…
Frequent Cannabis Use Linked With Higher Seizure Burden in Drug-Resistant Epilepsy
medical cannabis research: A small EMU cohort found frequent cannabis users with drug-resistant epilepsy had more focal to bilateral tonic-clonic seizures and greater medication burden, but the study cannot prove cannabis caused worse epilepsy. It keeps…
