Cannabis Pharmacokinetics Review: THC, CBD, Dosing
This paper is a broad evidence review of human pharmacokinetic studies on THC and CBD. It helps clarify how route, formulation, food, sex, drug interactions, and patient factors can meaningfully change absorption and exposure. Its main limitation is that…
Flipping the Switch to LED Grow Lights: Adjustments and Refinements
LED grow lights cannabis cultivation is transforming medical cannabis production by influencing cannabinoid and terpene profiles. Adjustments and refinements in cultivation methods are essential to maintain product consistency and therapeutic efficacy.…
Can Cannabis Replace Opioids for Chronic Pain? What We Know and What Remains Uncertain
This 2025 narrative review explores cannabinoid analgesia mechanisms and their role in chronic pain management. It highlights biological plausibility and clinical evidence supporting cannabinoids for neuropathic and arthritis pain. However, significant…
Only Five Trials Found: Cannabinoids for Post-Surgery Pain Remain an Open Question
The focus on cannabinoids acute postoperative pain reveals only five trials with contradictory results. This scarcity of data prevents meta-analytic evaluations and clinical recommendations. More standardized research is essential to clarify their role…
Mapping the Clinical Trial Landscape for Cannabinoids in Neurology: A Registry-Based Systematic Review
This systematic review of cannabinoid clinical trials neurological disorders highlights research focused on Multiple Sclerosis, Fibromyalgia, and Parkinson's Disease. It reveals challenges due to inconsistent protocols and dosing across studies. The…
Cannabis and the Heart and Vessels: What the Science Actually Says
This 2024 narrative review explores cannabinoid involvement in atherosclerosis and other vascular diseases, highlighting both therapeutic promise and evidentiary gaps. The endocannabinoid system plays a complex role in vascular biology through multiple…
Cannabinoids Show Short-Term Promise for Sleep Apnea, But Evidence Remains Too Thin for Clinical Use
A cannabinoids sleep apnea systematic review shows mostly positive short-term outcomes, including reduced apnea hypopnea index and improved daytime sleepiness. However, adverse events occurred in 70-80% of participants, raising safety concerns. The…
Opioids and Cannabinoids for Neurologic Pain: What Neurologists Need to Know in 2024
This 2024 CME review focuses on opioid therapy neurologic pain, synthesizing current evidence and guidelines for neurologists. It highlights risks of abrupt opioid tapering and the investigational role of cannabinoids. The review supports a cautious,…
Therapeutic use of cannabinoids in age-related pain: Current evidence and clinical perspectives.
The therapeutic use of cannabinoids in age-related pain offers promising alternatives for older adults suffering from chronic conditions. This approach targets underlying inflammation and pain mechanisms unique to aging. Current evidence supports…
Investigating Cannabinoids for Inflammation and Sickle Cell Disease Pain
This protocol outlines a randomized controlled trial investigating dronabinol sickle cell disease pain management. The study evaluates cannabinoids for inflammation and pain reduction. It aims to provide evidence for safer alternatives to opioids in…
