Cannabidiol Urine Concentrations in Athletes: Effects of Daily Use and Exercise
CBD urine concentrations in athletes climbed to detectable levels after just ten weeks of daily broad-spectrum supplement use at 150 mg per day. Exercise further amplified the effect, raising the risk that trace cannabinoids like CBG and CBDV would…
Cannabidiol Effects on Glutamate and Learning in Psychosis Prevention
Cannabidiol clinical trials psychosis research reveal that a single dose of CBD modulates hippocampal glutamate and prefrontal activation during memory tasks. This suggests CBD's potential to normalize disrupted brain circuitry in early psychosis. These…
Endocannabinoid System Research: Cannabidiol’s Impact on Glucose Tolerance & Gut Health in Obese Adults
This pilot study examined cannabidiol gut microbiome obesity effects and found no significant improvement in glucose tolerance in sedentary overweight adults. While animal studies suggested metabolic benefits, these were not replicated here. Larger…
Cannabidiol Effects on Cortical Excitability: Evidence from a Randomized, Double-Blind, Placebo-Controlled Study
This clinical trial evaluated CBD anti seizure activity and found no direct effect on cortical excitability or sedation in healthy adults. The study suggests CBD's benefit may depend on interactions with other drugs like clobazam. These findings…
Cannabis Dosing in Family Medicine: Evidence-Based Care for Endocannabinoid System Regulation
CBD dominant edibles anxiety relief shows significant promise in reducing anxiety symptoms. Cannabis dosing for anxiety varies by product type and cannabinoid composition. This evidence-based approach supports family medicine care focused on…
How CBD Interfered With HIV Entry Across Multiple Immune Cells
CBD HIV transmission prevention research published in Mucosal Immunology found that cannabidiol disrupted HIV-1 infection across multiple immune cell populations in laboratory and human tissue models. Researchers at Institut Cochin identified a…
Mechanistic Pathways Linking Cannabidiol, Hemp Seed Oil and Black Sesame Oil in Hyperarousal Insomnia: A Narrative Review.
A narrative review examines how CBD hyperarousal insomnia mechanistic pathways may involve endocannabinoid, inflammatory, and autonomic system modulation. While mechanistically plausible, this theoretical framework requires clinical validation before…
Comparative Pharmacokinetics and Safety of Cannabidiol in a Powder Formulation, CBtru
This study on cbd powder formulation pharmacokinetics reveals comparable bioavailability to traditional oil-based CBD products. It highlights formulation-dependent food effects on absorption in healthy adults. While bioequivalence is established,…
The effects of cannabidiol on sleep disturbances within a sample of high trait worriers: A double-blind, randomized placebo controlled trial.
This CBD sleep disturbances trial investigates cannabidiol's effects on sleep in individuals with high trait worry. The study is a double-blind, randomized placebo controlled trial. It provides important insights into CBD's role in managing sleep…
CBD for Brain Tumor Anxiety: What This Trial Found
Advanced cannabis clinical evidence shows that CBD for brain tumor anxiety did not outperform placebo in reducing anxiety or depressive symptoms. This early-terminated randomized trial enrolled adults with primary brain tumors and clinically relevant…