Cannabis stigma and symptom management considerations in cancer survivors: a mixed-methods exploration of patient perspectives.
This study explores cannabis stigma symptom management among cancer survivors. It assesses patient attitudes and perceptions regarding cannabis use for symptom relief. Findings reveal generally positive views and minimal stigma from healthcare providers.
Cannabigerol Induces ER Stress-Mediated Apoptosis and Ferroptosis in Pancreatic Cancer
Cannabigerol pancreatic cancer cells research reveals dual mechanisms of cell death: apoptosis and ferroptosis. This study highlights the role of endoplasmic reticulum stress via the IRE1α-XBP1 axis. These findings provide promising preclinical insights…
The dual roles of natural cannabidiol in combating oxidative stress and inflammation: A potential intestinal guardian.
CBD antioxidant anti-inflammatory effects play a crucial role in protecting the intestinal tract by reducing oxidative stress and inflammation. This natural compound modulates key pathways to preserve gut barrier integrity. Understanding these effects…
The association between major depressive disorder and cannabis use disorder: A meta-analysis and meta-regression analysis.
This meta-analysis on major depressive disorder cannabis use meta-analysis reveals significant prevalence of co-occurring conditions. It highlights the importance of integrated screening and treatment. Understanding this relationship is crucial for…
Therapeutic Potential of Acidic Cannabinoids: An Update
Acidic cannabinoids therapeutic potential is gaining attention for their unique biological activities. These compounds, including THCA and CBDA, show promise in neuroprotection and anti-inflammatory effects. Current research emphasizes the need for more…
Phase 1 Open-Label Pilot Trial of H4 dTMS for Cannabis Use Disorder
Deep repetitive transcranial magnetic stimulation cannabis use is being studied as a novel intervention for cannabis use disorder. This phase 1 open-label pilot trial evaluates safety and feasibility. The study targets adults with moderate-to-severe…
Reducing Severe Breathlessness with Dronabinol in Severe COPD Patients
The dronabinol COPD breathlessness trial investigates synthetic THC's potential to alleviate severe dyspnea in advanced COPD patients. This randomized, double-blinded crossover study evaluates breathing discomfort and lung function. Results will inform…
Understanding Cannabis Use for Symptom Management in Cancer Patients
Cannabis use cancer symptom management is increasingly common among patients undergoing treatment. The National Cancer Institute supports studies to evaluate both benefits and harms. These efforts aim to provide rigorous data to guide clinical…
Systematic Review: Medical Cannabis for Diabetic Peripheral Neuropathy
This systematic review evaluated medical cannabis diabetic neuropathy interventions in randomized controlled trials. Evidence shows potential pain relief benefits for diabetic peripheral neuropathy. The review highlights cautious optimism for cannabis…
Assessing Bias in Substance Use Disorder Diagnosis Related to Trauma and Genetics
This article discusses substance use disorder trauma diagnostic assessment focusing on biases in standard criteria. Childhood adversity and genetic liability influence how symptoms are reported. Understanding these biases is key to improving SUD…