Skip to content
CED Clinic
Contact Us Book Consultation GLP-1 Care
-
Subscribe to our newsletter & never miss our best posts. Subscribe Now!
  • Facebook
  • X
  • Email
  • Instagram
  • YouTube
  • Substack
  • Dr Caplan’s Book
CED Clinic CED Clinic CED Clinic

Medicinal cannabis is changing the face of clinical medicine. We are the leaders of that change.

CED Clinic CED Clinic CED Clinic

Medicinal cannabis is changing the face of clinical medicine. We are the leaders of that change.

  • 📍 Main Menu
    • Home
    • CED Clinic Heart: Our Values
    • Learn More: CED Clinic
    • Contact us
      • Leave a Message
      • Request Telemedicine Visit
    • Meet Dr. Caplan
      • Dr Caplan on Social Media
      • Dr Caplan's Substack
      • Dr Caplan's Podcast
      • Dr Caplan's Book: Doctor-Approved Cannabis Handbook
    • Meet Erin Caplan, NP
    • Ask Dr Caplan (public Q&A)
    • Discussion Forums
    • SiteMap
  • Patient Care
    • New Patients - Welcome!
      • Book a Virtual Appointment
      • Intake Form
      • How to Get a Medical Marijuana Card (in MA)
      • Qualifying Conditions
      • Ailments That Cannabis Treats
      • Testimonials
      • Patient Stories
      • Adult Cannabis Care
      • Autism, Behavior & Language Help
    • Before & After Apppointments
      • Request a Virtual Visit
      • Your Cannabis Journey
      • Your First Visit
      • Registration Information
      • Caregiver Information
      • After Registration
      • Which Products Are For You?
    • Cannabis & Seniors
      • 💜 Caregiver Support for Seniors
      • Seniors & Healthy Aging
      • Support for Caregiver of Seniors
      • Cannabis & Seniors: A New Chapter in Comfort
      • Cancer & Terminal Illness Support
      • End-of-Life Planning
      • Blog: Rising Cannabis Use in Older Adults
    • Pediatrics & Adolescents
      • Pediatric Care at CED Clinic
      • Pediatrics: Safety, Evidence & Risks
      • Cannabis for Young People: FAQ
      • 5 Benefits of Pediatric Cannabis Certification
      • Learn about Pedi & Adolescent Care
      • 10 Ways Cannabis Supports Children’s Behavior
      • Children & Behavior Support
      • Safe Dosing for Kids
      • Complex Pediatric Care
    • Sponsor a Visit (Give a Gift of Care)
    • Discounts at CED
      • Lottery for a Free Consultation
      • Discounts, Coupons, and Free Consultations
      • Discounts at Dispensaries (MA)
    • GLP-1 Weight Management
    • Health Quiz: Are You Healthy?
  • Education
    • Practical Tips + Guidance
      • Travel With Cannabis
      • COA Guide & Lab Safety
      • Fixing Your Cannabis Tolerance
      • Why Cannabis Works
      • Smart Cannabis Dosing: Sweet Spot?
      • Cannabis Myths + Blind Spots
      • How to Talk to Your Doc about Cannabis
      • Slow Medicine: How Cannabis Heals Over Time
      • Why The War on Pot Rages
      • Feeling Too High?
      • Cannabis & Mental Health Truths
      • Cannabis Cough: The Basics
      • Science of The Cannabis Cough
      • What To Do: Feeling Too Racy
      • Weed Anxiety Explained: Paranoia, Panic & Relief
      • Why Aren’t Edibles Don't Work for You?
      • When to Pause
      • Cannabis Hyperemesis Syndrome (CHS): What to Know
    • Health & Wellness
      • Cannabis & Health (general)
      • Choosing Cannabis
      • Tips for Maximizing Effectiveness
      • Cannabis & Metabolism: Be Amazed!
      • Cannabis for Sleep
      • Cannabis for Stress
      • Cannabis for Pain
      • Topicals Guide
      • Future of Cannabis
    • Learn by Illness or Condition
      • Custom Cannabis Protocol
      • Mental Health & Neurological Disorders
      • ADHD: A Guide to Focus, Calm, and Control
      • Crohn’s and Gut Health: Relief Strategies
      • Gastrointestinal & Autoimmune Conditions
      • Dermatological & Skin Conditions
      • Chronic Pain & Inflammation
      • Women’s Health & Hormonal Conditions
      • Pregnancy & Cannabis, Explained
      • Sleep Disorders & Circadian Rhythm Issues
      • Pain Management with Cannabis
      • Autism & Behavior: Expert Guidance for Families
      • Post-Surgical & Injury Recovery
      • Substance Dependence & Withdrawal Support
    • Learn about Products
      • Types of Cannabis Sold
      • CBD Strength Guide
      • Cannabis Tolerance: Management
      • Topical Cannabis Products: Guide to Uses, Benefits & DIY
      • Unique Cannabinoids: Beyond THC & CBD
      • Vaporizing Cannabis: Safer, Effective Consumption
    • Best Ways To Take Cannabis
      • Cannabis FAQs (basic)
      • Start Here
      • Cannabis Therapy Guidance
      • Dosage & Usage Guide
      • Nebulized Cannabis Guide
      • Topicals & Lotions
      • Tinctures & Oils
      • Cannabis Edibles & Capsules
      • Inhalables & Vaporization
    • Educational Resources
      • Dr Caplan's Book Website
        • Personalized, Signed Copy
        • My Book (Amazon)
        • Each Book Dedication is Unique!
      • FAQ Encyclopedia
      • Dr Caplan's Classroom
        • Book Diagrams + CaplanCannabis Site (free)
        • Video Library
        • Handouts & Guides
        • AI Book Review
        • Spotify: Green Table Talk Podcast
        • YouTube
        • Dr Caplan's Book (Order Now - Amazon!)
      • Cannabis Basics Overview
      • The Problems Cannabis Helps Us Manage
      • Endocannabinoid System
      • Cannabis Science
      • CED Cannabis Literature Library
      • Patient Care & Findings
      • Patient Insights
    • Guide: How to Buy Cannabis Flower
    • FAQ (Cannabis Encyclopedia)
    • Popular Blogs: 2026
      • Long-Term Effects of Cannabis
      • Reset Your Cannabis Tolerance
      • Weed Anxiety Explained: A Doctor’s Guide to Paranoia, Panic & Relief
      • 5 Reasons CBD CBG Topicals For Eczema Care is Amazing
      • Cannabis for Sleep
      • Slow Medicine: How Cannabis Heals Over Time
      • Why Aren’t Edibles Working for You?
      • When Cannabis Might NOT Be Right for You
      • Women’s Health & Hormonal Conditions
      • Cannabis for Stress
      • Cannabis for ADHD: A Guide to Focus, Calm, and Control
      • Too High? What To Do
      • Moldy Marijuana: MA recalls moldy flower
    • CED Favorites
      • Video: Cannabis Tolerance Explained
      • Plant Nurition Explained
      • Light THC & CBD Picks
      • High-Potency Cannabis Guide
      • Sugar-Free Cannabis Options
      • Cannabis & Your Heart
      • Cannabis and Psychosis
      • Vaginal Suppositories Page
      • Rectal Suppositories Page
      • Medical Cannabis Crossroads
      • Cannabis and Heart Health
      • Is Weed Addictive? Dependence vs Addiction
      • Cannabis and Menopause
      • Cannabis & Aging
      • CBD & Liver Enzymes
      • How Cannabis Works Differently
      • Emergence: How Wholes Outthink Parts
      • Our New Post-Covid Baseline
    • Non-Cannabis Writing
      • Social Capacity vs Identity: Connection
      • AI in Medicine Explained
      • Tylenol & Autism Debate
      • Power of Clicks and Likes
      • Rethinking Diagnosis in Kids
  • Partner with Dr Caplan
    • Partner on Education & Research
    • Work with Dr Caplan
    • Media Inquiries
    • Interview Dr. Caplan
    • Book Dr. Caplan to Speak
    • Clinical Cannabis Education Program
    • Modular (Custom) Professional Education
    • Volunteer at CED (Social Impact Work)
    • Cannabis Business Consulting
    • Building Big Data
    • Promote With CED Clinic
  • Resources, Supplies, Events
    • Share YOUR Story
    • Trusted Resources & Products
    • Shop Products: Gummies, Drinks, Oils, Flower...
    • Handmade Glass
    • Myriams CBD
    • Outside Resources
    • Past Events
    • Dispensary Highlights
    • Fireside Chats
  • 📍 Main Menu
    • Home
    • CED Clinic Heart: Our Values
    • Learn More: CED Clinic
    • Contact us
      • Leave a Message
      • Request Telemedicine Visit
    • Meet Dr. Caplan
      • Dr Caplan on Social Media
      • Dr Caplan's Substack
      • Dr Caplan's Podcast
      • Dr Caplan's Book: Doctor-Approved Cannabis Handbook
    • Meet Erin Caplan, NP
    • Ask Dr Caplan (public Q&A)
    • Discussion Forums
    • SiteMap
  • Patient Care
    • New Patients - Welcome!
      • Book a Virtual Appointment
      • Intake Form
      • How to Get a Medical Marijuana Card (in MA)
      • Qualifying Conditions
      • Ailments That Cannabis Treats
      • Testimonials
      • Patient Stories
      • Adult Cannabis Care
      • Autism, Behavior & Language Help
    • Before & After Apppointments
      • Request a Virtual Visit
      • Your Cannabis Journey
      • Your First Visit
      • Registration Information
      • Caregiver Information
      • After Registration
      • Which Products Are For You?
    • Cannabis & Seniors
      • 💜 Caregiver Support for Seniors
      • Seniors & Healthy Aging
      • Support for Caregiver of Seniors
      • Cannabis & Seniors: A New Chapter in Comfort
      • Cancer & Terminal Illness Support
      • End-of-Life Planning
      • Blog: Rising Cannabis Use in Older Adults
    • Pediatrics & Adolescents
      • Pediatric Care at CED Clinic
      • Pediatrics: Safety, Evidence & Risks
      • Cannabis for Young People: FAQ
      • 5 Benefits of Pediatric Cannabis Certification
      • Learn about Pedi & Adolescent Care
      • 10 Ways Cannabis Supports Children’s Behavior
      • Children & Behavior Support
      • Safe Dosing for Kids
      • Complex Pediatric Care
    • Sponsor a Visit (Give a Gift of Care)
    • Discounts at CED
      • Lottery for a Free Consultation
      • Discounts, Coupons, and Free Consultations
      • Discounts at Dispensaries (MA)
    • GLP-1 Weight Management
    • Health Quiz: Are You Healthy?
  • Education
    • Practical Tips + Guidance
      • Travel With Cannabis
      • COA Guide & Lab Safety
      • Fixing Your Cannabis Tolerance
      • Why Cannabis Works
      • Smart Cannabis Dosing: Sweet Spot?
      • Cannabis Myths + Blind Spots
      • How to Talk to Your Doc about Cannabis
      • Slow Medicine: How Cannabis Heals Over Time
      • Why The War on Pot Rages
      • Feeling Too High?
      • Cannabis & Mental Health Truths
      • Cannabis Cough: The Basics
      • Science of The Cannabis Cough
      • What To Do: Feeling Too Racy
      • Weed Anxiety Explained: Paranoia, Panic & Relief
      • Why Aren’t Edibles Don't Work for You?
      • When to Pause
      • Cannabis Hyperemesis Syndrome (CHS): What to Know
    • Health & Wellness
      • Cannabis & Health (general)
      • Choosing Cannabis
      • Tips for Maximizing Effectiveness
      • Cannabis & Metabolism: Be Amazed!
      • Cannabis for Sleep
      • Cannabis for Stress
      • Cannabis for Pain
      • Topicals Guide
      • Future of Cannabis
    • Learn by Illness or Condition
      • Custom Cannabis Protocol
      • Mental Health & Neurological Disorders
      • ADHD: A Guide to Focus, Calm, and Control
      • Crohn’s and Gut Health: Relief Strategies
      • Gastrointestinal & Autoimmune Conditions
      • Dermatological & Skin Conditions
      • Chronic Pain & Inflammation
      • Women’s Health & Hormonal Conditions
      • Pregnancy & Cannabis, Explained
      • Sleep Disorders & Circadian Rhythm Issues
      • Pain Management with Cannabis
      • Autism & Behavior: Expert Guidance for Families
      • Post-Surgical & Injury Recovery
      • Substance Dependence & Withdrawal Support
    • Learn about Products
      • Types of Cannabis Sold
      • CBD Strength Guide
      • Cannabis Tolerance: Management
      • Topical Cannabis Products: Guide to Uses, Benefits & DIY
      • Unique Cannabinoids: Beyond THC & CBD
      • Vaporizing Cannabis: Safer, Effective Consumption
    • Best Ways To Take Cannabis
      • Cannabis FAQs (basic)
      • Start Here
      • Cannabis Therapy Guidance
      • Dosage & Usage Guide
      • Nebulized Cannabis Guide
      • Topicals & Lotions
      • Tinctures & Oils
      • Cannabis Edibles & Capsules
      • Inhalables & Vaporization
    • Educational Resources
      • Dr Caplan's Book Website
        • Personalized, Signed Copy
        • My Book (Amazon)
        • Each Book Dedication is Unique!
      • FAQ Encyclopedia
      • Dr Caplan's Classroom
        • Book Diagrams + CaplanCannabis Site (free)
        • Video Library
        • Handouts & Guides
        • AI Book Review
        • Spotify: Green Table Talk Podcast
        • YouTube
        • Dr Caplan's Book (Order Now - Amazon!)
      • Cannabis Basics Overview
      • The Problems Cannabis Helps Us Manage
      • Endocannabinoid System
      • Cannabis Science
      • CED Cannabis Literature Library
      • Patient Care & Findings
      • Patient Insights
    • Guide: How to Buy Cannabis Flower
    • FAQ (Cannabis Encyclopedia)
    • Popular Blogs: 2026
      • Long-Term Effects of Cannabis
      • Reset Your Cannabis Tolerance
      • Weed Anxiety Explained: A Doctor’s Guide to Paranoia, Panic & Relief
      • 5 Reasons CBD CBG Topicals For Eczema Care is Amazing
      • Cannabis for Sleep
      • Slow Medicine: How Cannabis Heals Over Time
      • Why Aren’t Edibles Working for You?
      • When Cannabis Might NOT Be Right for You
      • Women’s Health & Hormonal Conditions
      • Cannabis for Stress
      • Cannabis for ADHD: A Guide to Focus, Calm, and Control
      • Too High? What To Do
      • Moldy Marijuana: MA recalls moldy flower
    • CED Favorites
      • Video: Cannabis Tolerance Explained
      • Plant Nurition Explained
      • Light THC & CBD Picks
      • High-Potency Cannabis Guide
      • Sugar-Free Cannabis Options
      • Cannabis & Your Heart
      • Cannabis and Psychosis
      • Vaginal Suppositories Page
      • Rectal Suppositories Page
      • Medical Cannabis Crossroads
      • Cannabis and Heart Health
      • Is Weed Addictive? Dependence vs Addiction
      • Cannabis and Menopause
      • Cannabis & Aging
      • CBD & Liver Enzymes
      • How Cannabis Works Differently
      • Emergence: How Wholes Outthink Parts
      • Our New Post-Covid Baseline
    • Non-Cannabis Writing
      • Social Capacity vs Identity: Connection
      • AI in Medicine Explained
      • Tylenol & Autism Debate
      • Power of Clicks and Likes
      • Rethinking Diagnosis in Kids
  • Partner with Dr Caplan
    • Partner on Education & Research
    • Work with Dr Caplan
    • Media Inquiries
    • Interview Dr. Caplan
    • Book Dr. Caplan to Speak
    • Clinical Cannabis Education Program
    • Modular (Custom) Professional Education
    • Volunteer at CED (Social Impact Work)
    • Cannabis Business Consulting
    • Building Big Data
    • Promote With CED Clinic
  • Resources, Supplies, Events
    • Share YOUR Story
    • Trusted Resources & Products
    • Shop Products: Gummies, Drinks, Oils, Flower...
    • Handmade Glass
    • Myriams CBD
    • Outside Resources
    • Past Events
    • Dispensary Highlights
    • Fireside Chats
Subscribe
Close

Search

Exclusive
Study Shows Sharp Increase in Rate of Unintentional Ingestions of Recreational Drugs ...
August 27, 2026
Study Shows Sharp Increase in Rate of Unintentional Ingestions of Recreational Drugs …
Cannabinoid Hyperemesis Syndrome | Cannabis
August 27, 2026
Cannabinoid Hyperemesis Syndrome | Cannabis
DEA releases cannabis rescheduling hearing transcript (Newsletter: August 26, 2026)
August 27, 2026
DEA releases cannabis rescheduling hearing transcript (Newsletter: August 26, 2026)
A transient mitochondrial switch underlies long lasting effects of adolescent cannabis
August 27, 2026
A transient mitochondrial switch underlies long lasting effects of adolescent cannabis
New York Office of Cannabis Management and Montefiore Einstein Open Registration for ...
August 27, 2026
New York Office of Cannabis Management and Montefiore Einstein Open Registration for …
Drug Treatment Admissions For Marijuana Are Highest In States Where It Remains Illegal ...
August 27, 2026
Drug Treatment Admissions For Marijuana Are Highest In States Where It Remains Illegal …
Medical Marijuana Linked to Significant Improvements in Chronic Pain, Anxiety and PTSD ...
August 27, 2026
Medical Marijuana Linked to Significant Improvements in Chronic Pain, Anxiety and PTSD …
Effect of Cannabinoids use on Symptoms of Restless Leg Syndrome among Adults
August 27, 2026
Effect of Cannabinoids use on Symptoms of Restless Leg Syndrome among Adults
Two new conditions now eligible for treatment with medical cannabis
August 27, 2026
Two new conditions now eligible for treatment with medical cannabis
Marijuana use up, alcohol use down: Are Americans trading one for the other?
August 27, 2026
Marijuana use up, alcohol use down: Are Americans trading one for the other?
cannabis vegetable tofu gyoza finished recipe styled as the emotional anchor with warm editorial food photography
August 27, 2026
Cannabis Vegetable Tofu Gyoza Recipe
Cannabis Legalization Outcomes: 329-Study Review
August 27, 2026
Cannabis Legalization Outcomes: What 329 Studies Found
Agitation in Dementia Can Be Helped by Medical Cannabis, Study Suggests - Springfield News-Sun
August 27, 2026
Agitation in Dementia Can Be Helped by Medical Cannabis, Study Suggests – Springfield News-Sun
Terpenes 101: A Guide to Cannabis Terpenes
August 27, 2026
Terpenes 101: A Guide to Cannabis Terpenes
Oxford (LSE:OCTP) — Why Is Clinical Development So Different From The Rest Of Cannabis Trade?
August 27, 2026
Oxford (LSE:OCTP) — Why Is Clinical Development So Different From The Rest Of Cannabis Trade?
Study: Health-Related Work Absences Drop 7% in States with Medical Cannabis Access
August 27, 2026
Study: Health-Related Work Absences Drop 7% in States with Medical Cannabis Access
CDC wants medical cannabis question on federal health survey (Newsletter: August 27, 2026)
August 27, 2026
CDC wants medical cannabis question on federal health survey (Newsletter: August 27, 2026)
CBD Autism Trial: Facial Expression Recognition and Theory of Mind | CBD oil autism social cognition
August 26, 2026
CBD Oil and Autism: What a New Randomized Trial Shows About Social Cognition
MedCanDem Trial: THC CBD Oil Dementia Agitation Results
August 26, 2026
THC/CBD Oil for Dementia Agitation: What the MedCanDem Trial Found
cannabis spinach dill spanakopita triangles finished recipe styled as the emotional anchor with warm editorial food photography
August 26, 2026
Cannabis Spinach Dill Spanakopita Triangles Recipe
Review Finds Cannabis Compounds Show Strong Anticancer Effects Against Cervical Cancer Cells
August 26, 2026
Review Finds Cannabis Compounds Show Strong Anticancer Effects Against Cervical Cancer Cells
a pile of brown bugs sitting on top of a rock
August 26, 2026
Onthophagus taurus anandamide
New conditions eligible for medical cannabis use in Illinois
August 26, 2026
New conditions eligible for medical cannabis use in Illinois
Sickle cell, PMOS added to list of medical cannabis-eligible conditions - Jacksonville Journal-Courier
August 26, 2026
Sickle cell, PMOS added to list of medical cannabis-eligible conditions – Jacksonville Journal-Courier
Common condition that impacts millions of Illinois women can now be treated with medical marijuana
August 26, 2026
Common condition that impacts millions of Illinois women can now be treated with medical marijuana
Research documents arranged on clipboards, illustrating national public health data review
August 26, 2026
Cannabis Use Disorder Is Rising Among US Adults
DEA Marijuana Decision Moves Closer — What Schedule III Could Mean For Michigan
August 26, 2026
DEA Marijuana Decision Moves Closer — What Schedule III Could Mean For Michigan
Premature Atrial Contractions Reduced on Inhaled Cannabis Use Days
August 26, 2026
Premature Atrial Contractions Reduced on Inhaled Cannabis Use Days
Illinois Adds Two New Medical Marijuana Qualifying Conditions
August 26, 2026
Illinois Adds Two New Medical Marijuana Qualifying Conditions
Marijuana's Health Benefits and Risks: What the Research Actually Says
August 26, 2026
Marijuana’s Health Benefits and Risks: What the Research Actually Says
Illinois IDPH adds sickle cell disease and PMOS to medical cannabis qualifying conditions
August 26, 2026
Illinois IDPH Adds Sickle Cell Disease and PMOS to Medical Cannabis Qualifying Conditions
Home/Cannabis Science/Opioid Use Disorder Among Cervical Fusion Inpatients: Trends, Complications, and Resource Use in a Retrospective National Inpatient Sample Analysis, 2016-2022.
Opioid Use Disorder Among Cervical Fusion Inpatients: Trends, Complications, and Resource Use in a Retrospective National Inpatient Sample Analysis, 2016-2022.
Cannabis Science

Opioid Use Disorder Among Cervical Fusion Inpatients: Trends, Complications, and Resource Use in a Retrospective National Inpatient Sample Analysis, 2016-2022.

By Benjamin Caplan, MD
4 Min Read
Comments Off on Opioid Use Disorder Among Cervical Fusion Inpatients: Trends, Complications, and Resource Use in a Retrospective National Inpatient Sample Analysis, 2016-2022.
CED Clinical Relevance  #60Notable Clinical Interest
Evidence Brief | CED ClinicOpioid use disorder prevalence among cervical fusion patients increased from 2016-2022, with OUD patients experiencing higher complication rates and resource utilization.
Opioid Use DisorderCervical FusionSpine SurgeryPerioperative CareComplications

Table of Contents

  • Opioid Use Disorder Among Cervical Fusion Inpatients: Trends, Complications, and Resource Use in a Retrospective National Inpatient Sample Analysis, 2016-2022.
    • FAQ
        • What is the prevalence of opioid use disorder among cervical fusion patients?
        • Are patients with opioid use disorder at higher risk for complications after cervical fusion surgery?
        • How does opioid use disorder affect healthcare resource utilization in cervical fusion patients?
        • What factors are associated with opioid use disorder in cervical fusion patients?
        • How should surgeons modify their approach when treating cervical fusion patients with opioid use disorder?
  • Newsletter Signup Form
      • Read next
      • Related

Opioid Use Disorder Among Cervical Fusion Inpatients: Trends, Complications, and Resource Use in a Retrospective National Inpatient Sample Analysis, 2016-2022.

Talk to Dr. Caplan

Want to apply this research to your own care?

30,000+ patients treated. Appointments in Massachusetts and via telemedicine.

Book a consultation →GLP-1 + cannabis program
BC

Dr. Benjamin Caplan, MD

Board-certified Family Medicine

20+ years in cannabis medicine. CMO, CED Clinic. Author, Penguin Random House. Principal Investigator in multiple studies.

Full bio →

Related reading

  • Conditions A–Z →
  • Cannabis & anxiety →
  • Cannabis & sleep →
  • Cannabinoid profiles →

Wherever you are

Dr. Caplan offers consultations for complex conditions and wellness needs. Patients from across the US and internationally are welcome.

Book a consultation →

Opioid use disorder prevalence among cervical fusion patients increased from 2016-2022, with OUD patients experiencing higher complication rates and resource utilization.

What This Study Teaches Us

This study documents the growing intersection of the opioid crisis with spine surgery populations. It demonstrates that opioid use disorder is becoming increasingly prevalent among patients requiring cervical fusion and establishes clear associations between OUD status and worse clinical outcomes.

Why This Matters

Spine surgeons increasingly encounter patients with established opioid dependence, requiring modified perioperative pain management strategies. Understanding OUD prevalence trends and associated risks helps inform preoperative counseling, surgical planning, and postoperative care protocols.

Study Snapshot
Study Type Retrospective Cohort Study
Population Adults undergoing elective inpatient cervical fusion surgery, 2016-2022
Intervention Cervical fusion surgery in patients with and without opioid use disorder
Comparator Cervical fusion patients without opioid use disorder
Primary Outcome Temporal trends in opioid use disorder prevalence, complications, and resource utilization
Key Finding Increasing prevalence of OUD among cervical fusion patients with higher complication rates
Journal Global Spine Journal
Year 2024
Clinical Bottom Line

Opioid use disorder is an increasingly common comorbidity in cervical fusion patients and correlates with higher complication rates and resource use. This finding necessitates systematic approaches to identifying and managing OUD in spine surgery populations.

What This Paper Does Not Show

The abstract provides no data on specific complication rates, length of stay differences, or pain management strategies used. It does not establish causality between OUD and complications, nor does it provide guidance on optimal perioperative management approaches.

Where This Paper Deserves Skepticism

Administrative coding for OUD may underestimate true prevalence due to documentation practices and stigma. The study cannot distinguish between pre-existing OUD and iatrogenic dependence, and retrospective design limits assessment of pain management effectiveness or patient-reported outcomes.

Dr. Caplan's Take
This confirms what many spine surgeons already observe clinically – OUD is becoming more common in surgical populations and complicates care. However, without specific outcome data or management strategies, this mainly quantifies a known problem rather than providing actionable solutions for perioperative care.
What a Careful Reader Should Take Away

OUD prevalence in cervical fusion patients is rising and associated with worse outcomes, but this study primarily establishes the scope of the problem rather than solutions. Clinicians should anticipate encountering OUD more frequently and prepare appropriate perioperative protocols, while recognizing that optimal management strategies remain undefined.

Join the Conversation

Have a question about how this applies to your situation? Ask Dr. Caplan →

Want to discuss this topic with other patients and caregivers? Join the forum discussion →

Have thoughts on this? Share it:

X Share on Xin Share on LinkedIn? Share on BlueSky? Follow on Instagram? Read more on Substack? Subscribe via RSS

FAQ

What is the prevalence of opioid use disorder among cervical fusion patients?

Based on this retrospective analysis of the National Inpatient Sample from 2016-2022, the prevalence of opioid use disorder (OUD) among adult patients undergoing elective cervical fusion has been increasing over this time period. The study used ICD-10-CM codes to identify OUD cases and found a notable upward trend in prevalence.

Are patients with opioid use disorder at higher risk for complications after cervical fusion surgery?

Yes, patients with OUD experience significantly higher complication rates following cervical fusion surgery compared to those without OUD. The study used multivariable logistic regression analysis to demonstrate that OUD is independently associated with increased medical complications during hospitalization.

How does opioid use disorder affect healthcare resource utilization in cervical fusion patients?

Patients with OUD require significantly more healthcare resources during their cervical fusion hospitalization. This includes longer hospital stays, higher healthcare costs, and different discharge disposition patterns compared to patients without OUD.

What factors are associated with opioid use disorder in cervical fusion patients?

The study identified several independent risk factors associated with OUD through multivariable analysis. These factors can help clinicians identify high-risk patients who may benefit from enhanced perioperative planning and monitoring.

How should surgeons modify their approach when treating cervical fusion patients with opioid use disorder?

Given the increased complication rates and resource utilization in OUD patients, surgeons should consider enhanced perioperative planning and multidisciplinary care coordination. This may include optimized pain management strategies, extended monitoring protocols, and specialized discharge planning to address the unique needs of this patient population.








CED Clinic logo
Physician-Led, Whole-Person Care
A doctor who takes the time to truly understand you.
Personal care that starts with listening and is guided by experience and ingenuity.
Health, Longevity, Wellness
One-on-One Cannabis Guidance
Metabolic Balance

Leave a Message
Metabolic Care
Medical Consulting
Cannabis Care


Dr. Benjamin Caplan

  • Newsletter Signup Form

    Enter your email address to subscribe to our newsletter.
  • Should be Empty:

Read next

Cannabis Legalization Outcomes: What 329 Studies Found

Related

Tags:

Cervical Fusionopioid use disorderSpine Surgery
Author

Benjamin Caplan, MD

Follow Me
Other Articles
ced pexels 29612816
Previous

The cannabidiol (CBD): Tetrahydrocanabinol (THC) concentration ratio is critical for neuroprotection and recovery following traumatic brain injury.

Beyond Epilepsy Control: Repurposing Antiepileptic Drugs in Central Nervous System Tumor Therapy.
Next

Beyond Epilepsy Control: Repurposing Antiepileptic Drugs in Central Nervous System Tumor Therapy.

Book Now Intake Form
Dr. Benjamin Caplan, MD Learn About Dr. Caplan
Copyright 2026 — CED Clinic. All rights reserved.

Questions about this research?

Talk to Dr. Caplan →
CED Clinic
CED Clinic Home
Explore
Cannabis Science
Research & Clinical
Cannabis News
Policy, Humor & News
Metabolic Health
GLP-1 Care & Science
Cannabis Recipes
Infused Foods & Drinks
Book an Appointment Contact CED Clinic
Recent Posts
Loading…
MENU