THC, CBD: Topic Summary Hub
🔍 CED Perspective Lens: THC, CBD
Dr. Benjamin Caplan, MDTHC, CBD represents a fundamental pillar in medical endocannabinoid therapy. Every guide in this hub synthesizes peer-reviewed evidence, clinical dosing strategies, and physiological mechanism maps curated specifically for patient care and clinical guidance.
📚 Clinical Resources & Guides (10 Full Guides)
Common Cannabinoids
An in-depth look at the common cannabinoids in cannabis, including THC and CBD, how they differ chemically, and where each shows medical potential.
The Biochemical Pathways of THC and CBD
How THC and CBD are absorbed, metabolized, and cleared, and why the two cannabinoids follow different biochemical routes through the body.
Advantages of CBD vs Advantages of THC: A Comprehensive Guide
A side by side comparison of what CBD and THC each do well, where they overlap, and how the balance between them shapes a treatment plan.
Transformation of Delta-9 THC from a Chemistry Perspective
The chemical transformations of delta-9 THC, from the plant through metabolism, explained step by step.
The Decarboxylation Process for THC from a Chemical Perspective
How heat converts THCA to THC through decarboxylation, why it matters for edibles and inhalation, and the chemistry behind the reaction.
THC Glucuronidation and Secretion
The role of glucuronidation in THC metabolism and elimination, and how the body packages THC metabolites for excretion.
Time to Peak THC and CBD Levels in Plasma: Fasting and Non-Fasting
How long it takes THC and CBD to reach peak blood levels, and how a full or empty stomach changes the timing.
Ratio of Total THC to CBD: Fasting and Non-Fasting
How fasting and eating change the ratio of THC to CBD in the body, and what that means for dosing.
The Influence of THC on Sleep and Sleep Stages
How THC affects NREM and REM sleep by dose, with a dose by stage table and a comparison with common sleep medications.
The Influence of CBD on Sleep and Sleep Stages
How CBD may affect each stage of sleep by dose, from sleep onset to REM, compared with antihistamines, THC, and prescription sleep aids.