All WIN-55,212-2 groups showed a noticeable decrease in vessel lumen diameter compared to the control group, with the multiple dosing group exhibiting a decrease that was on average ~3% greater than that of the respective acute dosing groups.
Endocannabinoid System in Autism Development Research
Clinical Takeaway Cannabis exposure during the peripregnancy period was associated with increased behavioral problems and developmental delays in children, with stronger associations observed in children who had autism spectrum disorder symptoms compared...
Endocannabinoid System Clinical Research Guide
Clinical Takeaway Clinical Takeaway Prenatal alcohol exposure frequently occurs alongside other substance use, and understanding these concurrent patterns is essential for identifying pregnant individuals at highest risk for adverse fetal and developmental...
Endocannabinoid System in Autism Development
Clinical Takeaway Maternal cannabis use during pregnancy was associated with increased behavioral and developmental concerns in children, with stronger associations observed in children who had autism spectrum disorder symptoms compared to those...
Endocannabinoid System and Pregnancy: Clinical Evidence
Clinical Takeaway Prenatal alcohol exposure frequently occurs alongside other substance use, with the combination potentially increasing risks to fetal development beyond alcohol alone. Understanding these concurrent use patterns helps clinicians identify pregnant...
Endocannabinoid System in Child Development
Clinical Takeaway Clinical Takeaway: Maternal cannabis use during peripregnancy (3 months before conception through delivery) showed associations with behavioral and developmental outcomes in young children, with different patterns observed between children with...
Endocannabinoid System and Prenatal Cannabis: Clinical Research
Clinical Takeaway Clinical Takeaway Pregnant women who use cannabis have offspring with modestly increased risks of autism spectrum disorder (30% higher) and ADHD (13% higher) based on observational data, though these associations...
Endocannabinoid System Clinical Research: Pregnancy Alcohol Use Study
Clinical Takeaway Clinical Takeaway Prenatal alcohol exposure frequently occurs alongside other substance use, creating compounded developmental risks that clinicians must assess together rather than in isolation. Understanding these concurrent use patterns helps...
Endocannabinoid System and Child Development
Clinical Takeaway Maternal cannabis use during the three months before conception through delivery was associated with behavioral and developmental differences in children, with effects varying based on whether children had autism spectrum...
Endocannabinoid System Research: Clinical Evidence Guide
Clinical Takeaway Clinical Takeaway Prenatal alcohol exposure frequently occurs alongside use of other substances like cannabis, tobacco, and opioids, complicating efforts to isolate alcohol's specific effects on fetal development. Understanding these concurrent...